Title : Estimation of mandarin peel oil-induced cytotoxicity and genotoxicity in human normal fibroblast and cancerous prostate cell lines.

Pub. Date : 2021 Feb

PMID : 33054537






1 Functional Relationships(s)
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1 The time dependent induction of DNA breaks demonstrated in PC3 cells treated with MPO safe concentration stimulated ROS generation and apoptotic DNA damage through increased expression of tumor suppressor p53 and Bax genes and decreased expression of Bcl2 and MDM2 genes. ros tumor protein p53 Homo sapiens