Title : Inhibition of NADPH Oxidases Activity by Diphenyleneiodonium Chloride as a Mechanism of Senescence Induction in Human Cancer Cells.

Pub. Date : 2020 Dec 8

PMID : 33302580






1 Functional Relationships(s)
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1 We demonstrated that the temporal treatment of HCT116 and MCF-7 cancer cells (both p53 wild-type) with DPI caused induction of senescence, that was correlated with decreased level of ROS and upregulation of p53/p21 proteins. ros tumor protein p53 Homo sapiens