| 1 |
34597388 | Propionate attenuates atherosclerosis by immune-dependent regulation of intestinal cholesterol metabolism. | 2022 Feb 10 |
1 |
| 2 |
35063734 | Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption. | 2022 Feb 15 |
4 |
| 3 |
35359877 | The NPC1L1 Gene Exerts a Notable Impact on the Reduction of Low-Density Lipoprotein Cholesterol in Response to Hyzetimibe: A Factorial-Designed Clinical Trial. | 2022 |
1 |
| 4 |
35390434 | Genetic variation and intestinal cholesterol absorption in humans: A systematic review and a gene network analysis. | 2022 Apr |
1 |
| 5 |
32368969 | Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab. | 2021 |
4 |
| 6 |
32853776 | A prospective mechanism and source of cholesterol uptake by Plasmodium falciparum-infected erythrocytes co-cultured with HepG2 cells. | 2021 Feb |
2 |
| 7 |
33167740 | Association of NPC1L1 and HMGCR Gene Polymorphisms with Major Adverse Cardiac and Cerebrovascular Events in Patients with Three-Vessel Disease. | 2021 Jun |
2 |
| 8 |
33671529 | Common Genetic Variations Involved in the Inter-Individual Variability of Circulating Cholesterol Concentrations in Response to Diets: A Narrative Review of Recent Evidence. | 2021 Feb 22 |
1 |
| 9 |
33760662 | NPC1L1-dependent transport of 27-alkyne cholesterol in intestinal epithelial cells. | 2021 May 1 |
6 |
| 10 |
33799730 | CYP7A1, NPC1L1, ABCB1, and CD36 Polymorphisms Are Associated with Increased Serum Coenzyme Q10 after Long-Term Supplementation in Women. | 2021 Mar 11 |
1 |
| 11 |
34067439 | Synthesis and Modeling of Ezetimibe Analogues. | 2021 May 22 |
2 |
| 12 |
34272236 | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake. | 2021 Jul |
9 |
| 13 |
34407950 | Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption. | 2021 Aug |
8 |
| 14 |
34428895 | Lycopene Reduces Cholesterol Absorption and Prevents Atherosclerosis in ApoE-/- Mice by Downregulating HNF-1α and NPC1L1 Expression. | 2021 Sep 8 |
1 |
| 15 |
34511128 | Expression and prognostic significance of Niemann-Pick C1-Like 1 in colorectal cancer: a retrospective cohort study. | 2021 Sep 12 |
1 |
| 16 |
34925816 | Lactobacillus mediates the expression of NPC1L1, CYP7A1, and ABCG5 genes to regulate cholesterol. | 2021 Dec |
2 |
| 17 |
31417158 | Selective Ah receptor modulators attenuate NPC1L1-mediated cholesterol uptake through repression of SREBP-2 transcriptional activity. | 2020 Feb |
5 |
| 18 |
32068819 | Association Between Genetically Proxied Inhibition of HMG-CoA Reductase and Epithelial Ovarian Cancer. | 2020 Feb 18 |
1 |
| 19 |
32410728 | Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. | 2020 May 15 |
6 |
| 20 |
32596471 | Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition. | 2020 Jun |
7 |
| 21 |
32860884 | Ezetimibe impairs transcellular lipid trafficking and induces large lipid droplet formation in intestinal absorptive epithelial cells. | 2020 Dec |
1 |
| 22 |
29466845 | Duodenal Niemann-Pick C1-like 1 expression was negatively correlated with liver X receptor expression in nonalcoholic fatty liver disease. | 2019 Jul |
2 |
| 23 |
30229515 | Identification of a Novel Potential Probiotic Lactobacillus plantarum FB003 Isolated from Salted-Fermented Shrimp and its Effect on Cholesterol Absorption by Regulation of NPC1L1 and PPARα. | 2019 Sep |
2 |
| 24 |
30773830 | NPC1L1-Targeted Cholesterol-Grafted Poly(β-Amino Ester)/pDNA Complexes for Oral Gene Delivery. | 2019 Apr |
1 |
| 25 |
30789754 | Mechanisms of Niemann-Pick type C1 Like 1 protein degradation in intestinal epithelial cells. | 2019 Apr 1 |
3 |
| 26 |
30994973 | Nonglucuronidated Ezetimibe Disrupts CD13- and CD64-Coassembly in Membrane Microdomains and Decreases Cellular Cholesterol Content in Human Monocytes/Macrophages. | 2019 Aug |
4 |
| 27 |
31049152 | The TICE Pathway: Mechanisms and Lipid-Lowering Therapies. | 2019 Jan-Mar |
6 |
| 28 |
31064810 | Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice. | 2019 Jul |
5 |
| 29 |
31098406 | Caffeine-free hawk tea lowers cholesterol by reducing free cholesterol uptake and the production of very-low-density lipoprotein. | 2019 |
2 |
| 30 |
31525874 | Xanthohumol Suppresses NPC1L1 Gene Expression through Downregulation of HNF-4α and Inhibits Cholesterol Uptake in Caco-2 Cells. | 2019 Oct 9 |
2 |
| 31 |
31545993 | Microalgal carotenoids and phytosterols regulate biochemical mechanisms involved in human health and disease prevention. | 2019 Dec |
1 |
| 32 |
31590417 | The Effect of Polyphenols on Hypercholesterolemia through Inhibiting the Transport and Expression of Niemann-Pick C1-Like 1. | 2019 Oct 6 |
3 |
| 33 |
31867479 | Computational Modeling Explains the Multi Sterol Ligand Specificity of the N-Terminal Domain of Niemann-Pick C1-Like 1 Protein. | 2019 Dec 17 |
1 |
| 34 |
31883528 | Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet. | 2019 Dec 28 |
1 |
| 35 |
29311470 | Associations between Lifestyle-Related Diseases and Transporters Involved in Intestinal Absorption and Biliary Excretion of Cholesterol. | 2018 |
2 |
| 36 |
29463265 | Fatty acids modulate the expression levels of key proteins for cholesterol absorption in Caco-2 monolayer. | 2018 Feb 20 |
1 |
| 37 |
29483961 | The prognostic value of Niemann-Pick C1-like protein 1 and Niemann-Pick disease type C2 in hepatocellular carcinoma. | 2018 |
2 |
| 38 |
29569242 | Egg-Yolk Sphingomyelin and Phosphatidylcholine Attenuate Cholesterol Absorption in Caco-2 Cells. | 2018 Feb |
2 |
| 39 |
29601818 | Hepatic NPC1L1 promotes hyperlipidemia in LDL receptor deficient mice. | 2018 May 15 |
1 |
| 40 |
29764733 | Genetic polymorphism of sterol transporters in children with future gallstones. | 2018 Sep |
2 |
| 41 |
29880681 | A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption. | 2018 Jun 8 |
2 |
| 42 |
30391500 | Ezetimibe inhibits dengue virus infection in Huh-7 cells by blocking the cholesterol transporter Niemann-Pick C1-like 1 receptor. | 2018 Dec |
3 |
| 43 |
28057006 | Bisphenol A promotes cholesterol absorption in Caco-2 cells by up-regulation of NPC1L1 expression. | 2017 Jan 6 |
4 |
| 44 |
28100881 | Transporters for the Intestinal Absorption of Cholesterol, Vitamin E, and Vitamin K. | 2017 Apr 3 |
1 |
| 45 |
28167864 | Ezetimibe reduces cholesterol content and NF-kappaB activation in liver but not in intestinal tissue in guinea pigs. | 2017 |
2 |
| 46 |
28315682 | N-terminal domain of the cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) is essential for α-tocopherol transport. | 2017 Apr 29 |
12 |
| 47 |
28478831 | Hepatitis C virus may have an entero-hepatic cycle which could be blocked with ezetimibe. | 2017 May |
1 |
| 48 |
28821575 | LDL switches the LRP6 internalization route from flotillin dependent to clathrin dependent in hepatic cells. | 2017 Oct 15 |
2 |
| 49 |
29106532 | Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer. | 2017 Dec 1 |
1 |
| 50 |
26761771 | Characterization of the NPC1L1 gene and proteome from an exceptional responder to ezetimibe. | 2016 Mar |
7 |