Title : Ezetimibe impairs transcellular lipid trafficking and induces large lipid droplet formation in intestinal absorptive epithelial cells.

Pub. Date : 2020 Dec

PMID : 32860884






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Ezetimibe inhibits Niemann-Pick C1-like 1 (NPC1L1) protein, which mediates intracellular cholesterol trafficking from the brush border membrane to the endoplasmic reticulum, where chylomicron assembly takes place in enterocytes or in the intestinal absorptive epithelial cells. Cholesterol NPC1 like intracellular cholesterol transporter 1 Homo sapiens