Title : Pathophysiological importance of bile cholesterol reabsorption: hepatic NPC1L1-exacerbated steatosis and decreasing VLDL-TG secretion in mice fed a high-fat diet.

Pub. Date : 2019 Dec 28

PMID : 31883528






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Indeed, transgenic mice with hepatic expression of human NPC1L1 under a liver-specific promoter (L1-Tg mice) developed steatosis with a high-fat diet (HFD) containing cholesterol within a few weeks. Cholesterol NPC1 like intracellular cholesterol transporter 1 Homo sapiens