Title : A prospective mechanism and source of cholesterol uptake by Plasmodium falciparum-infected erythrocytes co-cultured with HepG2 cells.

Pub. Date : 2021 Feb

PMID : 32853776






2 Functional Relationships(s)
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1 Collectively, our results support the possibility that cholesterol import by P. falciparum involves hepatocytes, and cholesterol uptake into the parasite occurs via NPC1L1 protein or an NPC1L1 homolog during the erythrocytic stages of the P. falciparum lifecycle. Cholesterol NPC1 like intracellular cholesterol transporter 1 Homo sapiens
2 Collectively, our results support the possibility that cholesterol import by P. falciparum involves hepatocytes, and cholesterol uptake into the parasite occurs via NPC1L1 protein or an NPC1L1 homolog during the erythrocytic stages of the P. falciparum lifecycle. Cholesterol NPC1 like intracellular cholesterol transporter 1 Homo sapiens