NAD

CD38 antigen ; Mus musculus







82 Article(s)
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1 35087020 Transfer of the longevity-associated variant of BPIFB4 gene rejuvenates immune system and vasculature by a reduction of CD38+ macrophages and NAD+ decline. 2022 Jan 27 1
2 35138178 The CD38 glycohydrolase and the NAD sink: implications for pathological conditions. 2022 Mar 1 2
3 35263032 CD38 inhibitor 78c increases mice lifespan and healthspan in a model of chronological aging. 2022 Apr 1
4 35441488 CD38 Drives Progress of Osteoarthritis by Affecting Cartilage Homeostasis. 2022 May 1
5 33010451 CD38 downregulation modulates NAD+ and NADP(H) levels in thermogenic adipose tissues. 2021 Jan 6
6 33385109 Targeting CD38-dependent NAD+ metabolism to mitigate multiple organ fibrosis. 2021 Jan 22 4
7 33871064 Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD. 2021 Jul 5
8 33893948 Neurogenic Potential of Implanted Neurospheres Is Regulated by Optogenetic Stimulation of Hippocampal Astrocytes Ex Vivo. 2021 Apr 1
9 34112762 CD38 deficiency alleviates Ang II-induced vascular remodeling by inhibiting small extracellular vesicle-mediated vascular smooth muscle cell senescence in mice. 2021 Jun 11 1
10 34493542 Critical Role of Astrocyte NAD+ Glycohydrolase in Myelin Injury and Regeneration. 2021 Oct 13 9
11 34539634 Mouse CD38-Specific Heavy Chain Antibodies Inhibit CD38 GDPR-Cyclase Activity and Mediate Cytotoxicity Against Tumor Cells. 2021 1
12 34637964 CD38 activation by monosodium urate crystals contributes to inflammatory responses in human and murine macrophages. 2021 Dec 3 5
13 34803499 CD38 Deficiency Protects Mice from High Fat Diet-Induced Nonalcoholic Fatty Liver Disease through Activating NAD+/Sirtuins Signaling Pathways-Mediated Inhibition of Lipid Accumulation and Oxidative Stress in Hepatocytes. 2021 3
14 32300965 Aging alters acetylation status in skeletal and cardiac muscles. 2020 Jun 1
15 32363189 CD38 Causes Autophagic Flux Inhibition and Cardiac Dysfunction Through a Transcriptional Inhibition Pathway Under Hypoxia/Ischemia Conditions. 2020 3
16 32572044 Nicotinamide riboside supplementation corrects deficits in oxytocin, sociability and anxiety of CD157 mutants in a mouse model of autism spectrum disorder. 2020 Jun 22 1
17 33020065 Cell Type-Specific Roles of CD38 in the Interactions of Isoniazid with NAD+ in the Liver. 2020 Dec 5
18 33082370 Deletion of CD38 and supplementation of NAD+ attenuate axon degeneration in a mouse facial nerve axotomy model. 2020 Oct 20 2
19 33120985 Novel Pathway of Adenosine Generation in the Lungs from NAD+: Relevance to Allergic Airway Disease. 2020 Oct 27 3
20 33326496 Distinct physical condition and social behavior phenotypes of CD157 and CD38 knockout mice during aging. 2020 7
21 31244614 Deletion of CD38 Suppresses Glial Activation and Neuroinflammation in a Mouse Model of Demyelination. 2019 3
22 29719225 A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline. 2018 May 1 3
23 29977153 CD38 Deficiency Promotes Inflammatory Response through Activating Sirt1/NF-κB-Mediated Inhibition of TLR2 Expression in Macrophages. 2018 1
24 30114710 CD38 Deficiency Protects Heart from High Fat Diet-Induced Oxidative Stress Via Activating Sirt3/FOXO3 Pathway. 2018 1
25 27518087 CD38 Knockout Mice Show Significant Protection Against Ischemic Brain Damage Despite High Level Poly-ADP-Ribosylation. 2017 Jan 5
26 27939939 CD38 in the pathogenesis of allergic airway disease: Potential therapeutic targets. 2017 Apr 2
27 28807785 Blocking the CD38/cADPR pathway plays a double-edged role in LPS stimulated microglia. 2017 Oct 11 1
28 27547294 CD38 Deficiency Protects the Heart from Ischemia/Reperfusion Injury through Activating SIRT1/FOXOs-Mediated Antioxidative Stress Pathway. 2016 1
29 27592202 Tissue-specific regulation of sirtuin and nicotinamide adenine dinucleotide biosynthetic pathways identified in C57Bl/6 mice in response to high-fat feeding. 2016 Nov 1
30 25828863 Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors. 2015 Apr 23 2
31 25893674 Alzheimer's disease pathology is attenuated in a CD38-deficient mouse model. 2015 Jul 5
32 26089537 Unconventional, adenosine-producing suppressor T cells induced by dendritic cells exposed to BPZE1 pertussis vaccine. 2015 Oct 1
33 26267483 Discovery of 4-Amino-8-quinoline Carboxamides as Novel, Submicromolar Inhibitors of NAD-Hydrolyzing Enzyme CD38. 2015 Sep 10 1
34 26287487 Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility. 2015 3
35 24578339 Basal CD38/cyclic ADP-ribose-dependent signaling mediates ATP release and survival of microglia by modulating connexin 43 hemichannels. 2014 Jun 1
36 23123323 Mitochondrial dysfunction causing cardiac sodium channel downregulation in cardiomyopathy. 2013 Jan 1
37 23172919 Flavonoid apigenin is an inhibitor of the NAD+ ase CD38: implications for cellular NAD+ metabolism, protein acetylation, and treatment of metabolic syndrome. 2013 Apr 5
38 22100343 NAD(P)H oxidase-dependent intracellular and extracellular O2•- production in coronary arterial myocytes from CD38 knockout mice. 2012 Jan 15 1
39 22293203 CD38 is a key enzyme for the survival of mouse microglial BV2 cells. 2012 Feb 24 2
40 22351627 Adenosine 5-diphosphate-ribose is a neural regulator in primate and murine large intestine along with β-NAD(+). 2012 Apr 15 1
41 22700727 CD38 deficiency in the tumor microenvironment attenuates glioma progression and modulates features of tumor-associated microglia/macrophages. 2012 Aug 1
42 23213344 Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype. 2012 1
43 21586363 Ectonucleotidases as regulators of purinergic signaling in thrombosis, inflammation, and immunity. 2011 1
44 21937766 Altered behavioral and metabolic circadian rhythms in mice with disrupted NAD+ oscillation. 2011 Aug 2
45 22033928 Connexin-43 hemichannels mediate cyclic ADP-ribose generation and its Ca2+-mobilizing activity by NAD+/cyclic ADP-ribose transport. 2011 Dec 30 2
46 19796917 A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes. 2010 Mar 1
47 20551293 Role of CD38, a cyclic ADP-ribosylcyclase, in morphine antinociception and tolerance. 2010 Sep 1 1
48 20638362 Mouse embryonic fibroblasts from CD38 knockout mice are resistant to oxidative stresses through inhibition of reactive oxygen species production and Ca(2+) overload. 2010 Aug 20 4
49 20975043 Extracellular NAD+ shapes the Foxp3+ regulatory T cell compartment through the ART2-P2X7 pathway. 2010 Nov 22 1
50 18931329 CD38 plays a dual role in allergen-induced airway hyperresponsiveness. 2009 Apr 1