Title : Genetic Ablation of CD38 Protects against Western Diet-Induced Exercise Intolerance and Metabolic Inflexibility.

Pub. Date : 2015

PMID : 26287487






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 CD38, a multi-functional membrane receptor and enzyme, consumes NAD+ to generate products such as cyclic-ADP-ribose. NAD CD38 antigen Mus musculus
2 CD38 knockout mice show elevated tissue and blood NAD+ level. NAD CD38 antigen Mus musculus
3 These animal model results suggest that elevation of tissue NAD+ through genetic ablation of CD38 can profoundly alter energy homeostasis in animals that are maintained on a calorically-excessive Western diet. NAD CD38 antigen Mus musculus