Tretinoin

cytochrome P450 family 26 subfamily A member 1 ; Homo sapiens







145 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35565751 CRABPs Alter all-trans-Retinoic Acid Metabolism by CYP26A1 via Protein-Protein Interactions. 2022 Apr 24 4
2 33472949 Cross-talk between YAP and RAR-RXR Drives Expression of Stemness Genes to Promote 5-FU Resistance and Self-Renewal in Colorectal Cancer Cells. 2021 Apr 2
3 33724958 Cardiac retinoic acid levels decline in heart failure. 2021 Apr 22 2
4 34122632 Sphingosine kinases are involved in the regulation of all-trans retinoic acid sensitivity of K562 chronic myeloid leukemia cells. 2021 Aug 4
5 34389675 Drivers and suppressors of triple-negative breast cancer. 2021 Aug 17 1
6 31744925 Correction to "Induction of CYP26A1 by Metabolites of Retinoic Acid: Evidence That CYP26A1 Is an Important Enzyme in the Elimination of Active Retinoids". 2020 Jan 2
7 31903789 Liposomal delivery of hydrophobic RAMBAs provides good bioavailability and significant enhancement of retinoic acid signalling in neuroblastoma tumour cells. 2020 Jul 3
8 32151018 Regulating Retinoic Acid Availability during Development and Regeneration: The Role of the CYP26 Enzymes. 2020 Mar 5 11
9 32251704 Development of an adverse outcome pathway for cranio-facial malformations: A contribution from in silico simulations and in vitro data. 2020 Jun 3
10 32258025 Inhibition of GSK3 Represses the Expression of Retinoic Acid Synthetic Enzyme ALDH1A2 via Wnt/β-Catenin Signaling in WiT49 Cells. 2020 1
11 30250298 Inhibition of 15-PGDH causes Kras-driven tumor expansion through prostaglandin E2-ALDH1 signaling in the pancreas. 2019 Feb 2
12 30737277 Ethanol promotes differentiation of embryonic stem cells through retinoic acid receptor-γ. 2019 Apr 5 2
13 30885956 Dendritic Cell Expression of Retinal Aldehyde Dehydrogenase-2 Controls Graft-versus-Host Disease Lethality. 2019 May 1 2
14 31039331 CYP26A1 gene promoter is a useful tool for reporting RAR-mediated retinoid activity. 2019 Jul 15 1
15 31419517 Biochemical and physiological importance of the CYP26 retinoic acid hydroxylases. 2019 Dec 7
16 29177441 De novo mutations in Caudal Type Homeo Box transcription Factor 2 (CDX2) in patients with persistent cloaca. 2018 Jan 15 2
17 29330906 Generating retinoic acid gradients by local degradation during craniofacial development: One cell's cue is another cell's poison. 2018 Feb 1
18 29337257 A comparison of the embryonic stem cell test and whole embryo culture assay combined with the BeWo placental passage model for predicting the embryotoxicity of azoles. 2018 Apr 1
19 28087565 Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes. 2017 Apr 1
20 28087752 Deficient retinoid-driven angiogenesis may contribute to failure of adult human lung regeneration in emphysema. 2017 Jun 3
21 28275201 Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions. 2017 May 1
22 28361034 Combinatorial Ranking of Gene Sets to Predict Disease Relapse: The Retinoic Acid Pathway in Early Prostate Cancer. 2017 1
23 28643469 ATRA Signaling Regulates the Expression of COL9A1 through BMP2-WNT4-RUNX1 Pathway in Antler Chondrocytes. 2017 Sep 1
24 28735443 Retinoic acid regulates avian lung branching through a molecular network. 2017 Dec 1
25 28754309 Retinoic acid, CYP26, and drug resistance in the stem cell niche. 2017 Oct 1
26 26009309 Elevated expression of the retinoic acid-metabolizing enzyme CYP26C1 in primary breast carcinomas. 2016 Mar 2
27 26374207 Expression of the retinoic acid catabolic enzyme CYP26B1 in the human brain to maintain signaling homeostasis. 2016 Jul 3
28 26747727 All-trans retinoic acid modulates Wnt3A-induced osteogenic differentiation of mesenchymal stem cells via activating the PI3K/AKT/GSK3β signalling pathway. 2016 Feb 15 1
29 26918322 Development and Characterization of Novel and Selective Inhibitors of Cytochrome P450 CYP26A1, the Human Liver Retinoic Acid Hydroxylase. 2016 Mar 24 4
30 26937021 Identification of Tazarotenic Acid as the First Xenobiotic Substrate of Human Retinoic Acid Hydroxylase CYP26A1 and CYP26B1. 2016 May 1
31 26999080 Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1. 2016 Mar 15 1
32 27242163 Optic nerve injury upregulates retinoic acid signaling in the adult frog visual system. 2016 Nov 1
33 27366899 Effect of NADPH-cytochrome P450 reductase on all-trans-retinoic acid efficacy and cytochrome P450 26A1 expression in human myeloid leukaemia HL-60 cells. 2016 Sep 2
34 27589347 Accelerated Skeletal Maturation in Disorders of Retinoic Acid Metabolism: A Case Report and Focused Review of the Literature. 2016 Nov 2
35 27590114 Normalizing Microbiota-Induced Retinoic Acid Deficiency Stimulates Protective CD8(+) T Cell-Mediated Immunity in Colorectal Cancer. 2016 Sep 20 1
36 27775549 Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance. 2016 Dec 1 1
37 25492813 Induction of CYP26A1 by metabolites of retinoic acid: evidence that CYP26A1 is an important enzyme in the elimination of active retinoids. 2015 5
38 25541526 Molecular recognition of CYP26A1 binding pockets and structure-activity relationship studies for design of potent and selective retinoic acid metabolism blocking agents. 2015 Mar 4
39 25915157 Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. 2015 Jun 20 1
40 26047326 All-Trans Retinoic Acid Activity in Acute Myeloid Leukemia: Role of Cytochrome P450 Enzyme Expression by the Microenvironment. 2015 3
41 26058854 The retinoic acid-metabolizing enzyme CYP26A1 upregulates fascin and promotes the malignant behavior of breast carcinoma cells. 2015 Aug 4
42 26233912 Role of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and Cancer. 2015 3
43 26365710 Design, synthesis, and biological evaluation of amide imidazole derivatives as novel metabolic enzyme CYP26A1 inhibitors. 2015 Oct 15 3
44 24608339 The expression and prognostic significance of retinoic acid metabolising enzymes in colorectal cancer. 2014 2
45 24642534 NADPH-cytochrome P450 reductase is regulated by all-trans retinoic acid and by 1,25-dihydroxyvitamin D3 in human acute myeloid leukemia cells. 2014 1
46 24667328 Cyp26 enzymes are required to balance the cardiac and vascular lineages within the anterior lateral plate mesoderm. 2014 Apr 3
47 24819304 Hepatocyte nuclear factor 4α (HNF4α) in coordination with retinoic acid receptors increases all-trans-retinoic acid-dependent CYP26A1 gene expression in HepG2 human hepatocytes. 2014 Oct 8
48 24821725 Retinoic acid and histone deacetylases regulate epigenetic changes in embryonic stem cells. 2014 Jul 11 1
49 25294402 Increased expression of the retinoic acid-metabolizing enzyme CYP26A1 during the progression of cervical squamous neoplasia and head and neck cancer. 2014 Oct 7 1
50 23441061 Expression of Ski can act as a negative feedback mechanism on retinoic acid signaling. 2013 Jun 1