Title : Physiologically Based Pharmacokinetic Model of All-trans-Retinoic Acid with Application to Cancer Populations and Drug Interactions.

Pub. Date : 2017 May

PMID : 28275201






1 Functional Relationships(s)
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1 The population-based PBPK model of atRA disposition incorporated saturable metabolic clearance of atRA, induction of CYP26A1 by atRA, and the absorption and distribution kinetics of atRA. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens