Title : Hedgehog and retinoid signaling alters multiple myeloma microenvironment and generates bortezomib resistance.

Pub. Date : 2016 Dec 1

PMID : 27775549






1 Functional Relationships(s)
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1 We previously showed that expression of CYP26 in BM stromal cells maintains a retinoic acid-low (RA-low) microenvironment that prevents the differentiation of normal and malignant hematopoietic cells. Tretinoin cytochrome P450 family 26 subfamily A member 1 Homo sapiens