Reactive Oxygen Species

ABL proto-oncogene 1, non-receptor tyrosine kinase ; Homo sapiens







44 Article(s)
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1 34953803 A bis-pyridinium fullerene derivative induces apoptosis through the generation of ROS in BCR-ABL-positive leukemia cells. 2022 Feb 5 5
2 35080463 Combined Host- and Pathogen-Directed Therapy for the Control of Mycobacterium abscessus Infection. 2022 Feb 23 2
3 35085070 Analyzing efficacy and safety of anti-fungal blue light therapy via kernel-based modeling the reactive oxygen species induced by light. 2022 Jan 27 1
4 33924068 Relationship between Oxidative Stress and Imatinib Resistance in Model Chronic Myeloid Leukemia Cells. 2021 Apr 20 2
5 34156283 Targeting FEN1 Suppresses the Proliferation of Chronic Myeloid Leukemia Cells Through Regulating Alternative End-Joining Pathways. 2021 Aug 1
6 33078787 Ultra-small platinum nanoparticles on gold nanorods induced intracellular ROS fluctuation to drive megakaryocytic differentiation of leukemia cells. 2020 Nov 10 1
7 31396300 Reactive Oxygen Species Are Involved in the Development of Gastric Cancer and Gastric Cancer-Related Depression through ABL1-Mediated Inflammation Signaling Pathway. 2019 4
8 29205725 Pleckstrin homology domain of p210 BCR-ABL interacts with cardiolipin to regulate its mitochondrial translocation and subsequent mitophagy. 2018 Jan 1
9 29859988 Taxodione induces apoptosis in BCR-ABL-positive cells through ROS generation. 2018 Aug 1
10 29975106 Extracellular vesicles transfer nuclear Abl-dependent and radiation-induced miR-34c into unirradiated cells to cause bystander effects. 2018 Sep 1 1
11 30297534 Pathologic Oxidation of PTPN12 Underlies ABL1 Phosphorylation in Hereditary Leiomyomatosis and Renal Cell Carcinoma. 2018 Dec 1 4
12 27566554 Oncogenic STAT5 signaling promotes oxidative stress in chronic myeloid leukemia cells by repressing antioxidant defenses. 2017 Jun 27 1
13 27904889 Reactive oxygen species in BCR-ABL1-expressing cells - relevance to chronic myeloid leukemia. 2017 1
14 28456613 E-Cadherin-Mediated Cell Contact Controls the Epidermal Damage Response in Radiation Dermatitis. 2017 Aug 1
15 27007600 Evolutionary Dynamics of Chronic Myeloid Leukemia Progression: the Progression-Inhibitory Effect of Imatinib. 2016 Jul 2
16 27666407 Depression accelerates the development of gastric cancer through reactive oxygen species‑activated ABL1 (Review). 2016 Nov 6
17 25620702 c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit. 2015 Feb 3 1
18 26106294 Reactive oxygen species trigger motoneuron death in non-cell-autonomous models of ALS through activation of c-Abl signaling. 2015 2
19 26513170 NOX5-L can stimulate proliferation and apoptosis depending on its levels and cellular context, determining cancer cell susceptibility to cisplatin. 2015 Nov 17 1
20 26697169 Role played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier function. 2015 Dec 1
21 26722260 Proteasome inhibitor MG-132 enhances histone deacetylase inhibitor SAHA-induced cell death of chronic myeloid leukemia cells by an ROS-mediated mechanism and downregulation of the Bcr-Abl fusion protein. 2015 Nov 2
22 24346354 Assessment of changes in membrane properties of platelets from patients with chronic myeloid leukaemia in different stages of the disease. 2014 Mar 1
23 24833663 NADPH oxidases as therapeutic targets in chronic myelogenous leukemia. 2014 Aug 1 1
24 23218026 Imatinib and Nilotinib inhibit Bcr-Abl-induced ROS through targeted degradation of the NADPH oxidase subunit p22phox. 2013 Feb 6
25 23320983 Association of XRCC1 gene polymorphisms with chronic myeloid leukemia in the population of Andhra Pradesh, India. 2013 May 1
26 23965958 The role of mitochondrial DNA damage and repair in the resistance of BCR/ABL-expressing cells to tyrosine kinase inhibitors. 2013 Aug 7 1
27 24765523 Modelling c-Abl Signalling in Activated Neutrophils: the Anti-inflammatory Effect of Seliciclib. 2013 Mar 1 2
28 22549737 Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells. 2012 Aug 5
29 21625221 NF-κB suppresses ROS levels in BCR-ABL(+) cells to prevent activation of JNK and cell death. 2011 Nov 10 4
30 21795709 Inhibition of protein-tyrosine phosphatase 1B (PTP1B) mediates ubiquitination and degradation of Bcr-Abl protein. 2011 Sep 16 2
31 20832390 Involvement of ROS in chlorogenic acid-induced apoptosis of Bcr-Abl+ CML cells. 2010 Dec 1 6
32 19295548 Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. 2009 Aug 7
33 19833721 Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium. 2009 Dec 11 3
34 18398719 BCR/ABL, DNA damage and DNA repair: implications for new treatment concepts. 2008 Apr 1
35 18524993 Up-regulation of WRN and DNA ligase IIIalpha in chronic myeloid leukemia: consequences for the repair of DNA double-strand breaks. 2008 Aug 15 2
36 20425353 Genomic instability: The cause and effect of BCR/ABL tyrosine kinase. 2007 May 1
37 16631755 Protein kinase PKC delta and c-Abl are required for mitochondrial apoptosis induction by genotoxic stress in the absence of p53, p73 and Fas receptor. 2006 May 15 1
38 16959615 Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate. 2006 Sep 3
39 15304390 BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks. 2004 Dec 1 2
40 12527798 Abrogation of the cell death response to oxidative stress by the c-Abl tyrosine kinase inhibitor STI571. 2003 Feb 1
41 12569093 Functional interaction between the c-Abl and Arg protein-tyrosine kinases in the oxidative stress response. 2003 Apr 11 5
42 11350980 Targeting of the c-Abl tyrosine kinase to mitochondria in the necrotic cell death response to oxidative stress. 2001 May 18 6
43 10770918 Activation of the cytoplasmic c-Abl tyrosine kinase by reactive oxygen species. 2000 Jun 9 1
44 10833515 The BCR/ABL tyrosine kinase induces production of reactive oxygen species in hematopoietic cells. 2000 Aug 11 8