Title : BCR/ABL oncogenic kinase promotes unfaithful repair of the reactive oxygen species-dependent DNA double-strand breaks.

Pub. Date : 2004 Dec 1

PMID : 15304390






2 Functional Relationships(s)
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1 We find that BCR/ABL-induced reactive oxygen species (ROSs) cause chronic oxidative DNA damage resulting in double-strand breaks (DSBs) in S and G(2)/M cell cycle phases. Reactive Oxygen Species ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens
2 We find that BCR/ABL-induced reactive oxygen species (ROSs) cause chronic oxidative DNA damage resulting in double-strand breaks (DSBs) in S and G(2)/M cell cycle phases. Reactive Oxygen Species ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens