Pub. Date : 2016 Jul
PMID : 27007600
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Constitutively activated Bcr-Abl signaling in CML creates high levels of reactive oxygen species (ROS) that produce 8-oxo-guanine in DNA; this is mutagenic and causes chronic phase (CP) progression to blast phase (BP). | Reactive Oxygen Species | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |
| 2 | Constitutively activated Bcr-Abl signaling in CML creates high levels of reactive oxygen species (ROS) that produce 8-oxo-guanine in DNA; this is mutagenic and causes chronic phase (CP) progression to blast phase (BP). | Reactive Oxygen Species | ABL proto-oncogene 1, non-receptor tyrosine kinase | Homo sapiens |