Serine

cyclin dependent kinase 2 ; Homo sapiens







97 Article(s)
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1 35115540 Cyclin B/CDK1 and Cyclin A/CDK2 phosphorylate DENR to promote mitotic protein translation and faithful cell division. 2022 Feb 3 1
2 33152171 Multi-kinase framework promotes proliferation and invasion of lung adenocarcinoma through activation of dynamin-related protein 1. 2021 Feb 1
3 33327806 Novel oxindole/benzofuran hybrids as potential dual CDK2/GSK-3β inhibitors targeting breast cancer: design, synthesis, biological evaluation, and in silico studies. 2021 Dec 1
4 33876395 HBx promotes hepatocarcinogenesis by enhancing phosphorylation and blocking ubiquitinylation of UHRF2. 2021 Jun 1
5 34140692 Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. 2021 Jun 2
6 34612580 CDK2 phosphorylation of Werner protein (WRN) contributes to WRN's DNA double-strand break repair pathway choice. 2021 Nov 2
7 32075913 Doxorubicin induces cardiomyocyte apoptosis and atrophy through cyclin-dependent kinase 2-mediated activation of forkhead box O1. 2020 Mar 27 1
8 32712628 Cell-cycle-dependent phosphorylation of RRM1 ensures efficient DNA replication and regulates cancer vulnerability to ATR inhibition. 2020 Aug 1
9 33414996 Identification of DHX36 as a tumour suppressor through modulating the activities of the stress-associated proteins and cyclin-dependent kinases in breast cancer. 2020 1
10 30589568 The phosphorylatable Ser320 of NF-YA is involved in DNA binding of the NF-Y trimer. 2019 Apr 1
11 30700607 S-Like-Phase Cyclin-Dependent Kinases Stabilize the Epstein-Barr Virus BDLF4 Protein To Temporally Control Late Gene Transcription. 2019 Apr 15 1
12 31350280 CDK2 regulates the NRF1/Ehmt1 axis during meiotic prophase I. 2019 Sep 2 1
13 31431461 The Cdk2-c-Myc-miR-571 Axis Regulates DNA Replication and Genomic Stability by Targeting Geminin. 2019 Oct 1 1
14 29157894 Selective inhibition reveals cyclin-dependent kinase 2 as another kinase that phosphorylates the androgen receptor at serine 81. 2018 Feb 1
15 29792216 HIV-1 Tat phosphorylation on Ser-16 residue modulates HIV-1 transcription. 2018 May 23 5
16 28934491 Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle. 2017 Sep 19 1
17 28980868 Exploring the role of CENP-A Ser18 phosphorylation in CIN and Tumorigenesis. 2017 1
18 26387543 Cyclin D1 promotes BRCA2-Rad51 interaction by restricting cyclin A/B-dependent BRCA2 phosphorylation. 2016 Jun 2 1
19 26701207 Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation. 2016 Jan 19 1
20 26771717 Cyclin-dependent kinase-mediated phosphorylation of breast cancer metastasis suppressor 1 (BRMS1) affects cell migration. 2016 2
21 26988343 The Functions of Serine 687 Phosphorylation of Human DNA Polymerase η in UV Damage Tolerance. 2016 Jun 4
22 27239332 Mimicking Cdk2 phosphorylation of Bcl-xL at Ser73 results in caspase activation and Bcl-xL cleavage. 2016 1
23 25548279 Cyclin E-CDK2 protein phosphorylates plant homeodomain finger protein 8 (PHF8) and regulates its function in the cell cycle. 2015 Feb 13 2
24 26139602 Cyclin-dependent kinase-mediated Sox2 phosphorylation enhances the ability of Sox2 to establish the pluripotent state. 2015 Sep 11 4
25 25364462 Phosphorylation of cyclin O, a novel cyclin family protein containing a cyclin-like domain, is involved in the activation of cyclin-dependent kinase 2. 2014 Dec 2
26 23184662 Phosphorylation of eukaryotic elongation factor 2 (eEF2) by cyclin A-cyclin-dependent kinase 2 regulates its inhibition by eEF2 kinase. 2013 Feb 1
27 23853094 Foxp3 protein stability is regulated by cyclin-dependent kinase 2. 2013 Aug 23 2
28 22072796 UHRF1 phosphorylation by cyclin A2/cyclin-dependent kinase 2 is required for zebrafish embryogenesis. 2012 Jan 6
29 22558186 CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response. 2012 1
30 22584582 Successive phosphorylation of p27(KIP1) protein at serine-10 and C terminus crucially controls its potency to inactivate Cdk2. 2012 Jun 22 3
31 22610972 The centrosomal protein Tax1 binding protein 2 is a novel tumor suppressor in hepatocellular carcinoma regulated by cyclin-dependent kinase 2. 2012 Nov 2
32 23028682 Phosphorylation of Rad9 at serine 328 by cyclin A-Cdk2 triggers apoptosis via interfering Bcl-xL. 2012 3
33 23140174 CDK2 regulates HIV-1 transcription by phosphorylation of CDK9 on serine 90. 2012 Nov 9 2
34 21148318 Cyclin-dependent kinase-mediated phosphorylation of RBP1 and pRb promotes their dissociation to mediate release of the SAP30·mSin3·HDAC transcriptional repressor complex. 2011 Feb 18 1
35 21308739 Interference with ER-α enhances the therapeutic efficacy of the selective CDK inhibitor roscovitine towards ER-positive breast cancer cells. 2011 Apr 1
36 20445224 Cdk2: a key regulator of the senescence control function of Myc. 2010 Apr 2
37 20466538 Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis. 2010 Jun 2
38 20530684 Cyclin E deregulation impairs mitotic progression through premature activation of Cdc25C. 2010 Jun 15 1
39 19150984 Identification and functional analysis of a novel cyclin e/cdk2 substrate ankrd17. 2009 Mar 20 3
40 19423708 Artemis regulates cell cycle recovery from the S phase checkpoint by promoting degradation of cyclin E. 2009 Jul 3 2
41 19478079 O-linked N-acetylglucosamine modification on CCAAT enhancer-binding protein beta: role during adipocyte differentiation. 2009 Jul 17 1
42 19686743 SKP2 and CKS1 promote degradation of cell cycle regulators and are associated with hepatocellular carcinoma prognosis. 2009 Nov 1
43 19703905 Cyclin A/cdk2 regulates adenomatous polyposis coli-dependent mitotic spindle anchoring. 2009 Oct 16 1
44 18183483 An unusual member of the Cdk family: Cdk5. 2008 May 1
45 18239466 Phosphorylation mediates Sp1 coupled activities of proteolytic processing, desumoylation and degradation. 2008 Mar 1 2
46 18332217 The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. 2008 Mar 10 2
47 18521083 Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells. 2008 Sep 11 1
48 18617527 Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells. 2008 Sep 12 1
49 17601773 Role of cdk2 in the sequential phosphorylation/activation of C/EBPbeta during adipocyte differentiation. 2007 Jul 10 1
50 17636466 Computational study of the phosphoryl transfer catalyzed by a cyclin-dependent kinase. 2007 1