Title : Cyclin E-CDK2 protein phosphorylates plant homeodomain finger protein 8 (PHF8) and regulates its function in the cell cycle.

Pub. Date : 2015 Feb 13

PMID : 25548279






2 Functional Relationships(s)
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1 By taking the approach of mass spectrometry, we identified that PHF8 Ser-844 is phosphorylated by cyclin E-CDK2. Serine cyclin dependent kinase 2 Homo sapiens
2 In addition, we found that cyclin E-CDK2-mediated phosphorylation of PHF8 Ser-844 promotes PHF8-dependent rRNA transcription in luciferase reporter assays and real-time PCR. Serine cyclin dependent kinase 2 Homo sapiens