Title : Interferon-γ-induced p27KIP1 binds to and targets MYC for proteasome-mediated degradation.

Pub. Date : 2016 Jan 19

PMID : 26701207






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We recently demonstrated that inhibition of Cdk2-mediated phosphorylation of Myc at Ser-62 pharmacologically or through interferon (IFN)-gamma-induced expression of p27(Kip1) (p27) repressed Myc"s activity to suppress cellular senescence and differentiation. Serine cyclin dependent kinase 2 Homo sapiens