Title : Phosphorylation mediates Sp1 coupled activities of proteolytic processing, desumoylation and degradation.

Pub. Date : 2008 Mar 1

PMID : 18239466






2 Functional Relationships(s)
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1 Our data show that Serine-59 regulates Sp1 proteolytic processing, and thereby provides a mechanism for the upregulation of Sp1-dependent transcription by CyclinA/cdk2 phosphorylation of Serine-59. Serine cyclin dependent kinase 2 Homo sapiens
2 Our data show that Serine-59 regulates Sp1 proteolytic processing, and thereby provides a mechanism for the upregulation of Sp1-dependent transcription by CyclinA/cdk2 phosphorylation of Serine-59. Serine cyclin dependent kinase 2 Homo sapiens