Fatty Acids

sterol regulatory element binding transcription factor 1 ; Mus musculus







100 Article(s)
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51 19119143 Suppression of 2,3-oxidosqualene cyclase by high fat diet contributes to liver X receptor-alpha-mediated improvement of hepatic lipid profile. 2009 Mar 6 2
52 19254698 Adiponectin suppresses hepatic SREBP1c expression in an AdipoR1/LKB1/AMPK dependent pathway. 2009 Apr 24 1
53 19713685 Chinese herbal medicine Yi-Gan-San decreases the lipid accumulation in mouse 3T3-L1 adipocytes by modulating the activities of transcription factors SREBP-1c and FoxO1. 2009 Sep 1
54 19731235 Modulation of glycosphingolipid metabolism significantly improves hepatic insulin sensitivity and reverses hepatic steatosis in mice. 2009 Nov 1
55 19801551 Fenofibrate simultaneously induces hepatic fatty acid oxidation, synthesis, and elongation in mice. 2009 Dec 4 1
56 18226595 Mouse Elovl-6 promoter is an SREBP target. 2008 Apr 4 1
57 18301758 Effect of synthetic dietary triglycerides: a novel research paradigm for nutrigenomics. 2008 Feb 27 1
58 18334917 Sterol regulatory element binding protein 1 interacts with pregnane X receptor and constitutive androstane receptor and represses their target genes. 2008 Apr 1
59 18812581 The effect of fasting on hepatic lipid accumulation and transcriptional regulation of lipid metabolism differs between C57BL/6J and BALB/cA mice fed a high-fat diet. 2008 Oct 1
60 17341595 Multiple roles of the nuclear receptors for oxysterols liver X receptor to maintain male fertility. 2007 May 1
61 17426115 Genome-wide analysis of PPARalpha activation in murine small intestine. 2007 Jul 18 1
62 17589797 Liver X receptors and epididymal epithelium physiology. 2007 Jul 1
63 17655900 Differential gene expression and lipid metabolism in fatty liver induced by acute ethanol treatment in mice. 2007 Sep 15 1
64 17662109 A transcription factor of lipid synthesis, sterol regulatory element-binding protein (SREBP)-1a causes G(1) cell-cycle arrest after accumulation of cyclin-dependent kinase (cdk) inhibitors. 2007 Sep 1
65 17919187 Sterol regulatory element-binding protein-1c and pancreatic beta-cell dysfunction. 2007 Nov 3
66 18070348 Gene expression and biological processes influenced by deletion of Stat3 in pulmonary type II epithelial cells. 2007 Dec 10 1
67 16144700 ACAT1 deficiency increases cholesterol synthesis in mouse peritoneal macrophages. 2006 Jun 1
68 16794015 Mouse sterol response element binding protein-1c gene expression is negatively regulated by thyroid hormone. 2006 Sep 1
69 16890542 Granuphilin is activated by SREBP-1c and involved in impaired insulin secretion in diabetic mice. 2006 Aug 1
70 16936198 Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in Akita and OVE26 mice with type 1 diabetes. 2006 Sep 2
71 15677507 Transgenic mice overexpressing nuclear SREBP-1c in pancreatic beta-cells. 2005 Feb 1
72 15913829 Signalling links in the liver: knitting SOCS with fat and inflammation. 2005 Jul 1
73 15949711 Transgenic mice overexpressing SREBP-1a under the control of the PEPCK promoter exhibit insulin resistance, but not diabetes. 2005 Jun 10 2
74 16046298 Regulation of renal lipid metabolism, lipid accumulation, and glomerulosclerosis in FVBdb/db mice with type 2 diabetes. 2005 Aug 1
75 16140264 Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice. 2005 Oct 28 1
76 16198472 Long chain fatty acyl-CoA synthetase 5 expression is induced by insulin and glucose: involvement of sterol regulatory element-binding protein-1c. 2005 Dec 1
77 16199872 Lipid synthetic transcription factor SREBP-1a activates p21WAF1/CIP1, a universal cyclin-dependent kinase inhibitor. 2005 Oct 1
78 16226915 Role of suppressors of cytokine signaling SOCS-1 and SOCS-3 in hepatic steatosis and the metabolic syndrome. 2005 Oct 1
79 15240880 Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse. 2004 Jul 13 1
80 12897148 Promoter-specific roles for liver X receptor/corepressor complexes in the regulation of ABCA1 and SREBP1 gene expression. 2003 Aug 2
81 12975478 PKClambda in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity. 2003 Sep 1
82 11782483 Diminished hepatic response to fasting/refeeding and liver X receptor agonists in mice with selective deficiency of sterol regulatory element-binding protein-1c. 2002 Mar 15 1
83 11792729 Dual regulation of mouse Delta(5)- and Delta(6)-desaturase gene expression by SREBP-1 and PPARalpha. 2002 Jan 1
84 11884293 Hepatic fatty acid synthesis is suppressed in mice with fatty livers due to targeted apolipoprotein B38.9 mutation. 2002 Mar 1 1
85 12196343 Accumulation of foam cells in liver X receptor-deficient mice. 2002 Aug 27 1
86 12481547 Sterol regulatory element-binding protein family as global regulators of lipid synthetic genes in energy metabolism. 2002 2
87 11287605 Identification of liver X receptor-retinoid X receptor as an activator of the sterol regulatory element-binding protein 1c gene promoter. 2001 May 1
88 11591434 Sterol regulatory element-binding proteins (SREBPs): transcriptional regulators of lipid synthetic genes. 2001 Nov 1
89 10771346 Neuronal localization of sterol regulatory element binding protein-1 in the rodent and primate brain: a light and electron microscopic immunocytochemical study. 2000 3
90 10772920 Anabolic function of the type II isozyme of hexokinase in hepatic lipid synthesis. 2000 Apr 21 1
91 10949029 Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice. 2000 Jul 1
92 11090130 Regulation of mouse sterol regulatory element-binding protein-1c gene (SREBP-1c) by oxysterol receptors, LXRalpha and LXRbeta. 2000 Nov 15 3
93 10194480 Disruption of LDL receptor gene in transgenic SREBP-1a mice unmasks hyperlipidemia resulting from production of lipid-rich VLDL. 1999 Apr 1
94 10514488 Increased levels of nuclear SREBP-1c associated with fatty livers in two mouse models of diabetes mellitus. 1999 Oct 15 2
95 10585467 Sterol regulatory element-binding protein-1 as a key transcription factor for nutritional induction of lipogenic enzyme genes. 1999 Dec 10 1
96 9600904 Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice. 1998 May 26 2
97 9765271 Characterization of the murine fatty acid transport protein gene and its insulin response sequence. 1998 Oct 16 1
98 9062341 Isoform 1c of sterol regulatory element binding protein is less active than isoform 1a in livers of transgenic mice and in cultured cells. 1997 Mar 1 1
99 8654925 ADD1/SREBP1 promotes adipocyte differentiation and gene expression linked to fatty acid metabolism. 1996 May 1 1
100 8833906 Overproduction of cholesterol and fatty acids causes massive liver enlargement in transgenic mice expressing truncated SREBP-1a. 1996 Oct 1 2