Title : Regulation of sterol regulatory element binding proteins in livers of fasted and refed mice.

Pub. Date : 1998 May 26

PMID : 9600904






2 Functional Relationships(s)
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1 The hepatic mRNAs for fatty acid biosynthetic enzymes increased 5- to 10-fold above nonfasted levels, a pattern that paralleled the changes in nuclear SREBP-1. Fatty Acids sterol regulatory element binding transcription factor 1 Mus musculus
2 We conclude that SREBPs are regulated by food consumption in the mouse liver and that the decline in nuclear SREBP-1c upon fasting may explain in part the decrease in mRNAs encoding enzymes of the fatty acid biosynthetic pathway. Fatty Acids sterol regulatory element binding transcription factor 1 Mus musculus