Title : Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice.

Pub. Date : 2000 Jul

PMID : 10949029






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Despite IRS-2 deficiency, insulin continues to stimulate production of SREBP-1c, a transcription factor that activates fatty acid synthesis. Fatty Acids sterol regulatory element binding transcription factor 1 Mus musculus