Title : Expression of asporin reprograms cancer cells to acquire resistance to oxidative stress.

Pub. Date : 2021 Mar

PMID : 33393151






1 Functional Relationships(s)
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1 ASPN induced expression of the HIF1alpha transcription factor, and upregulated LDHA and PDH-E1alpha, suggesting that ASPN reprograms HSC-43 cells to undergo anaerobic glycolysis and suppresses ROS generation in mitochondria, which was observed in another cell line HSC-44PE. Reactive Oxygen Species hypoxia inducible factor 1 subunit alpha Homo sapiens