Title : Elucidating Role of Reactive Oxygen Species (ROS) in Cisplatin Chemotherapy: A Focus on Molecular Pathways and Possible Therapeutic Strategies.

Pub. Date : 2021 Apr 19

PMID : 33921908






1 Functional Relationships(s)
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1 Genetic tools, such as small interfering RNA (siRNA) can down-regulate molecular pathways such as HIF-1alpha and Nrf2 to promote ROS levels, leading to CP sensitivity. Reactive Oxygen Species hypoxia inducible factor 1 subunit alpha Homo sapiens