Title : HIF-1α-BNIP3-mediated mitophagy in tubular cells protects against renal ischemia/reperfusion injury.

Pub. Date : 2020 Sep

PMID : 32829253






2 Functional Relationships(s)
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1 Results show that HIF-1alpha knockout significantly attenuated hypoxia/reoxygenation (H/R)-induced mitophagy, aggravated H/R-induced apoptosis, and increased the production of reactive oxygen species (ROS). Reactive Oxygen Species hypoxia inducible factor 1 subunit alpha Homo sapiens
2 Results show that HIF-1alpha knockout significantly attenuated hypoxia/reoxygenation (H/R)-induced mitophagy, aggravated H/R-induced apoptosis, and increased the production of reactive oxygen species (ROS). Reactive Oxygen Species hypoxia inducible factor 1 subunit alpha Homo sapiens