Title : MiR-125b attenuates retinal pigment epithelium oxidative damage via targeting Nrf2/HIF-1α signal pathway.

Pub. Date : 2022 Jan 1

PMID : 34875217






1 Functional Relationships(s)
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1 Additionally, the results identified that Nrf2 silence induced ROS accumulation enhances HIF-1alpha protein expression, while miR-125b could offset this effect via promoting HIF-1alpha protein degradation. Reactive Oxygen Species hypoxia inducible factor 1 subunit alpha Homo sapiens