Sorafenib

signal transducer and activator of transcription 3 ; Homo sapiens







71 Article(s)
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51 24086526 Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis. 2013 4
52 24331695 [Anti-proliferation effect of sorafenib in combination with 5-FU for hepatocellular carcinoma in vitro: antagonistic performance and mechanism]. 2013 Nov 3
53 21979753 Sorafenib-induced apoptosis of chronic lymphocytic leukemia cells is associated with downregulation of RAF and myeloid cell leukemia sequence 1 (Mcl-1). 2012 Feb 10 2
54 22180308 Dovitinib induces apoptosis and overcomes sorafenib resistance in hepatocellular carcinoma through SHP-1-mediated inhibition of STAT3. 2012 Feb 2
55 22278289 Targeting of distinct signaling cascades and cancer-associated fibroblasts define the efficacy of Sorafenib against prostate cancer cells. 2012 Jan 26 1
56 22406995 Sorafenib inhibits endogenous and IL-6/S1P induced JAK2-STAT3 signaling in human neuroblastoma, associated with growth suppression and apoptosis. 2012 May 7
57 22414764 Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells. 2012 Jul 1
58 22634008 Combined anti-tumor effects of IFN-α and sorafenib on hepatocellular carcinoma in vitro and in vivo. 2012 Jun 15 1
59 22787432 The monoclonal antibody CH12 enhances the sorafenib-mediated growth inhibition of hepatocellular carcinoma xenografts expressing epidermal growth factor receptor variant III. 2012 Jun 2
60 22871485 Blockade of STAT3 activation by sorafenib derivatives through enhancing SHP-1 phosphatase activity. 2012 Sep 2
61 22922424 Sorafenib down-regulates expression of HTATIP2 to promote invasiveness and metastasis of orthotopic hepatocellular carcinoma tumors in mice. 2012 Dec 1
62 20881478 Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation. 2011 Jan 8
63 21331764 Potent in vitro and in vivo antitumor activity of sorafenib against human intrahepatic cholangiocarcinoma cells. 2011 Jun 2
64 21531053 Sorafenib derivatives induce apoptosis through inhibition of STAT3 independent of Raf. 2011 Jul 3
65 21718664 Targeting STAT3 in hepatocellular carcinoma: sorafenib again…. 2011 Nov 1
66 20197401 Sorafenib inhibits STAT3 activation to enhance TRAIL-mediated apoptosis in human pancreatic cancer cells. 2010 Mar 5
67 20371721 Sorafenib induces growth arrest and apoptosis of human glioblastoma cells through the dephosphorylation of signal transducers and activators of transcription 3. 2010 Apr 10
68 20470863 Sorafenib exerts anti-glioma activity in vitro and in vivo. 2010 Jul 12 3
69 20490331 Sorafenib downregulates ERK/Akt and STAT3 survival pathways and induces apoptosis in a human neuroblastoma cell line. 2010 Apr 23 4
70 19821497 Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. 2009 Dec 6
71 19001435 Sorafenib inhibits signal transducer and activator of transcription 3 signaling associated with growth arrest and apoptosis of medulloblastomas. 2008 Nov 4