Title : Sorafenib exerts anti-glioma activity in vitro and in vivo.

Pub. Date : 2010 Jul 12

PMID : 20470863






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Sorafenib inhibited phosphorylation of signal transducer and activator of transcription 3 (Stat3) and expression of cyclins, D and E. Sorafenib signal transducer and activator of transcription 3 Homo sapiens
2 Sorafenib inhibited phosphorylation of signal transducer and activator of transcription 3 (Stat3) and expression of cyclins, D and E. Sorafenib signal transducer and activator of transcription 3 Homo sapiens
3 Furthermore, intracranial growth inhibition by sorafenib was accompanied by a significant reduction in ph-Stat3 (Tyr 705) levels. Sorafenib signal transducer and activator of transcription 3 Homo sapiens