Title : Epidermal growth factor receptor and HER-3 restrict cell response to sorafenib in hepatocellular carcinoma cells.

Pub. Date : 2012 Jul

PMID : 22414764






1 Functional Relationships(s)
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1 In cell lines cultured in 10% serum or treated with EGF, sorafenib alone inhibited phospho-STAT3 while it maintained or even increased phospho-ERK and/or phospho-AKT. Sorafenib signal transducer and activator of transcription 3 Homo sapiens