Serine

CREB regulated transcription coactivator 1 ; Mus musculus







102 Article(s)
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1 34985995 A Pseudorabies Virus Serine/Threonine Kinase, US3, Promotes Retrograde Transport in Axons via Akt/mToRC1. 2022 Mar 9 2
2 35020443 PP2A-dependent TFEB activation is blocked by PIKfyve-induced mTORC1 activity. 2022 Mar 1 3
3 35210408 SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis. 2022 Feb 24 1
4 35365663 Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification. 2022 Apr 1 1
5 35577075 Prolonged deprivation of arginine or leucine induces PI3K/Akt-dependent reactivation of mTORC1. 2022 May 13 1
6 33340488 In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition. 2021 Jan 21 4
7 33353667 Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32-Dependent D1 Dopamine Receptor Signaling and Behaviors. 2021 Jun 1 1
8 33401933 MTORC1-Regulated Metabolism Controlled by TSC2 Limits Cardiac Reperfusion Injury. 2021 Mar 5 1
9 33411856 TRK-Fused Gene (TFG), a protein involved in protein secretion pathways, is an essential component of the antiviral innate immune response. 2021 Jan 1
10 33881936 The regulation of polyamine pathway proteins in models of skeletal muscle hypertrophy and atrophy: a potential role for mTORC1. 2021 Jun 1 2
11 34102579 mTOR pathway and DNA damage response: A therapeutic strategy in cancer therapy. 2021 Aug 1
12 34130564 Cancer cells dysregulate PI3K/AKT/mTOR pathway activation to ensure their survival and proliferation: mimicking them is a smart strategy of gammaherpesviruses. 2021 Oct 1
13 34140692 Nuclear dihydroxyacetone phosphate signals nutrient sufficiency and cell cycle phase to global histone acetylation. 2021 Jun 1
14 34215308 Mammalian/mechanistic target of rapamycin (mTOR) complexes in neurodegeneration. 2021 Jul 2 1
15 34336098 Methionine Protects Mammary Cells against Oxidative Stress through Producing S-Adenosylmethionine to Maintain mTORC1 Signaling Activity. 2021 1
16 34341503 mTOR signaling mediates ILC3-driven immunopathology. 2021 Nov 1
17 34502151 The Amino Acid-mTORC1 Pathway Mediates APEC TW-XM-Induced Inflammation in bEnd.3 Cells. 2021 Aug 26 2
18 34531248 Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes. 2021 Sep 1
19 34544857 Interleukin-6 mediates PSAT1 expression and serine metabolism in TSC2-deficient cells. 2021 Sep 28 1
20 34673774 AKAP13 couples GPCR signaling to mTORC1 inhibition. 2021 Oct 2
21 32058690 Molecular Networking and Whole-Genome Analysis Aid Discovery of an Angucycline That Inactivates mTORC1/C2 and Induces Programmed Cell Death. 2020 Mar 20 1
22 32323755 AMPK activation protects astrocytes from hypoxia‑induced cell death. 2020 May 1
23 32392211 Depletion of Ric-8B leads to reduced mTORC2 activity. 2020 May 1
24 32444657 Enhanced skeletal muscle insulin sensitivity after acute resistance-type exercise is upregulated by rapamycin-sensitive mTOR complex 1 inhibition. 2020 May 22 1
25 32796887 Regulation of colonic epithelial cell homeostasis by mTORC1. 2020 Aug 14 1
26 32899613 Regulation of mTORC2 Signaling. 2020 Sep 4 1
27 33003310 Activation of Mechanistic Target of Rapamycin (mTOR) in Human Endothelial Cells Infected with Pathogenic Spotted Fever Group Rickettsiae. 2020 Sep 29 1
28 33009372 The mammalian target of rapamycin (mTOR) kinase mediates haloperidol-induced cataleptic behavior. 2020 Oct 2 1
29 33303821 Saturated fatty acids induce insulin resistance in podocytes through inhibition of IRS1 via activation of both IKKβ and mTORC1. 2020 Dec 10 1
30 30337688 mTOR kinase leads to PTEN-loss-induced cellular senescence by phosphorylating p53. 2019 Mar 1
31 30650200 Targeting mTORC1/2 with OSI-027 inhibits proliferation and migration of keloid keratinocytes. 2019 Mar 1
32 30700906 PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress. 2019 Feb 2
33 30795552 Targeting mTOR in Acute Lymphoblastic Leukemia. 2019 Feb 21 1
34 30819820 CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability. 2019 Apr 1 1
35 31085701 Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo. 2019 Jul 1 1
36 31112131 GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor. 2019 May 21 2
37 31113850 mTORC1 amplifies the ATF4-dependent de novo serine-glycine pathway to supply glycine during TGF-β1-induced collagen biosynthesis. 2019 May 21 1
38 31130364 Lysosome Positioning Influences mTORC2 and AKT Signaling. 2019 Jul 11 1
39 29253569 Activation of KGFR-Akt-mTOR-Nrf2 signaling protects human retinal pigment epithelium cells from Ultra-violet. 2018 Jan 15 1
40 29396369 Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1. 2018 Mar 1
41 29507340 MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. 2018 Mar 5 1
42 29849891 SGK1 Inhibits Autophagy in Murine Muscle Tissue. 2018 1
43 29883748 Inflammation-induced mTORC2-Akt-mTORC1 signaling promotes macrophage foam cell formation. 2018 Aug 1
44 29984036 Inhibition of Mast Cell Function and Proliferation by mTOR Activator MHY1485. 2018 Jun 1
45 30042494 Mitochondrial ROS-derived PTEN oxidation activates PI3K pathway for mTOR-induced myogenic autophagy. 2018 Nov 1
46 30240640 Serine Phosphorylation by mTORC1 Promotes IRS-1 Degradation through SCFβ-TRCP E3 Ubiquitin Ligase. 2018 Jul 27 2
47 30244971 Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides. 2018 Dec 4 1
48 30316815 PPARγ is a major regulator of branched-chain amino acid blood levels and catabolism in white and brown adipose tissues. 2018 Dec 1
49 27297361 A novel mechanism of mTORC1-mediated serine/glycine metabolism in osteosarcoma development. 2017 Jan 6
50 28004151 Reciprocal regulation of mTOR complexes in pancreatic islets from humans with type 2 diabetes. 2017 Apr 1