Title : Disruption of the Scaffolding Function of mLST8 Selectively Inhibits mTORC2 Assembly and Function and Suppresses mTORC2-Dependent Tumor Growth In Vivo.

Pub. Date : 2019 Jul 1

PMID : 31085701






1 Functional Relationships(s)
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1 mTOR is a serine/threonine kinase that acts in two distinct complexes, mTORC1 and mTORC2, and is dysregulated in many diseases including cancer. Serine CREB regulated transcription coactivator 1 Mus musculus