Title : SUMOylation of PDPK1 Is required to maintain glycolysis-dependent CD4 T-cell homeostasis.

Pub. Date : 2022 Feb 24

PMID : 35210408






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Loss of PDPK1 SUMOylation impeded its autophosphorylation at serine 241 (S241), thereby leading to hypoactivation of downstream mTORC1 signaling coupled with incompetence of cell proliferation. Serine CREB regulated transcription coactivator 1 Mus musculus