| 1 |
34850372 | Decreased efficacy of the ketamine and scopolamine-induced sustained antidepressant-like effects in rats receiving metformin. | 2022 Apr |
3 |
| 2 |
35132891 | Impact of metformin on tyrosine kinase inhibitor response in chronic myeloid leukemia. | 2022 Jun |
1 |
| 3 |
35301425 | Autistic-like behavior and cerebellar dysfunction in Bmal1 mutant mice ameliorated by mTORC1 inhibition. | 2022 Mar 17 |
1 |
| 4 |
35370636 | Fucoidan Alleviates Renal Fibrosis in Diabetic Kidney Disease via Inhibition of NLRP3 Inflammasome-Mediated Podocyte Pyroptosis. | 2022 |
1 |
| 5 |
33968030 | Metformin Modulates T Cell Function and Alleviates Liver Injury Through Bioenergetic Regulation in Viral Hepatitis. | 2021 |
3 |
| 6 |
34253170 | Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin. | 2021 Jul 12 |
10 |
| 7 |
34340683 | Correction to: Inhibition of mTORC1 through ATF4-induced REDD1 and Sestrin2 expression by Metformin. | 2021 Aug 2 |
1 |
| 8 |
34531248 | Mitochondrial reactive oxygen species trigger metformin-dependent antitumor immunity via activation of Nrf2/mTORC1/p62 axis in tumor-infiltrating CD8T lymphocytes. | 2021 Sep |
1 |
| 9 |
31926250 | Inhibition of mTORC1/P70S6K pathway by Metformin synergistically sensitizes Acute Myeloid Leukemia to Ara-C. | 2020 Feb 15 |
3 |
| 10 |
31945013 | Metformin attenuates cartilage degeneration in an experimental osteoarthritis model by regulating AMPK/mTOR. | 2020 Jan 16 |
1 |
| 11 |
32094377 | Metformin-induced suppression of IFN-α via mTORC1 signalling following seasonal vaccination is associated with impaired antibody responses in type 2 diabetes. | 2020 Feb 24 |
1 |
| 12 |
32535544 | Mechanisms of action of metformin in type 2 diabetes: Effects on mitochondria and leukocyte-endothelium interactions. | 2020 Jul |
1 |
| 13 |
32912901 | AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation. | 2020 Oct 1 |
6 |
| 14 |
33042258 | Pharmacological inhibition of mTORC1 increases CCKBR-specific tumor uptake of radiolabeled minigastrin analogue [177Lu]Lu-PP-F11N. | 2020 |
1 |
| 15 |
33178015 | Metformin: A Prospective Alternative for the Treatment of Chronic Pain. | 2020 |
1 |
| 16 |
30903363 | Metformin and Breast Cancer: Molecular Targets. | 2019 Jun |
1 |
| 17 |
31044492 | Metformin as an adjunct therapy for the treatment of moderate to severe acne vulgaris: A randomized open-labeled study. | 2019 Jul |
1 |
| 18 |
28606032 | Metformin, A New Era for an Old Drug in the Treatment of Immune Mediated Disease? | 2018 |
1 |
| 19 |
29162538 | Metformin promotes the proliferation and differentiation of murine preosteoblast by regulating the expression of sirt6 and oct4. | 2018 Mar |
1 |
| 20 |
29383869 | Metformin regulates metabolic and nonmetabolic pathways in skeletal muscle and subcutaneous adipose tissues of older adults. | 2018 Apr |
1 |
| 21 |
29482945 | Metformin influences drug sensitivity in pancreatic cancer cells. | 2018 May |
2 |
| 22 |
29554968 | Metformin induces autophagy and G0/G1 phase cell cycle arrest in myeloma by targeting the AMPK/mTORC1 and mTORC2 pathways. | 2018 Mar 20 |
2 |
| 23 |
29651002 | Metformin Decreases the Incidence of Pancreatic Ductal Adenocarcinoma Promoted by Diet-induced Obesity in the Conditional KrasG12D Mouse Model. | 2018 Apr 12 |
1 |
| 24 |
30150001 | Metformin as an Anticancer Agent. | 2018 Oct |
2 |
| 25 |
30206977 | A unified mitochondria mechanistic target of rapamycin acyl-coenzyme A dehydrogenase 10 signal relay modulation for metformin growth inhibition in human immortalized keratinocytes cells. | 2018 Sep 11 |
3 |
| 26 |
33435021 | Establishment of an ex Vivo Model of Nonalcoholic Fatty Liver Disease Using a Tissue-Engineered Liver. | 2018 Aug 13 |
1 |
| 27 |
27959383 | Combination of metformin and sorafenib suppresses proliferation and induces autophagy of hepatocellular carcinoma via targeting the mTOR pathway. | 2017 Jan |
2 |
| 28 |
28068384 | Hypoxia Regulates mTORC1-Mediated Keratinocyte Motility and Migration via the AMPK Pathway. | 2017 |
2 |
| 29 |
28089566 | Metformin Inhibits Hepatic mTORC1 Signaling via Dose-Dependent Mechanisms Involving AMPK and the TSC Complex. | 2017 Feb 7 |
4 |
| 30 |
28177677 | mTORC1 inhibitors rapamycin and metformin affect cardiovascular markers differentially in ZDF rats. | 2017 Mar |
2 |
| 31 |
28241849 | Metformin potentiates the effect of arsenic trioxide suppressing intrahepatic cholangiocarcinoma: roles of p38 MAPK, ERK3, and mTORC1. | 2017 Feb 28 |
3 |
| 32 |
28533436 | Metformin Synergizes with BCL-XL/BCL-2 Inhibitor ABT-263 to Induce Apoptosis Specifically in p53-Defective Cancer Cells. | 2017 Sep |
2 |
| 33 |
28755883 | Metformin: Insights into its anticancer potential with special reference to AMPK dependent and independent pathways. | 2017 Sep 15 |
2 |
| 34 |
28881582 | Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells. | 2017 Aug 1 |
2 |
| 35 |
29025968 | Activation of AMPK/mTORC1-Mediated Autophagy by Metformin Reverses Clk1 Deficiency-Sensitized Dopaminergic Neuronal Death. | 2017 Dec |
1 |
| 36 |
29027899 | Metformin extends C. elegans lifespan through lysosomal pathway. | 2017 Oct 13 |
2 |
| 37 |
25926238 | Hyperactive mTORC1 signaling is unaffected by metformin treatment in aged skeletal muscle. | 2016 Jan |
1 |
| 38 |
26551391 | Potential therapeutic effects of mTOR inhibition in atherosclerosis. | 2016 Nov |
2 |
| 39 |
27454290 | p53 coordinates decidual sestrin 2/AMPK/mTORC1 signaling to govern parturition timing. | 2016 Aug 1 |
2 |
| 40 |
27984715 | Metformin: Restraining Nucleocytoplasmic Shuttling to Fight Cancer and Aging. | 2016 Dec 15 |
1 |
| 41 |
25179820 | The anti-diabetic drug metformin inhibits vascular endothelial growth factor expression via the mammalian target of rapamycin complex 1/hypoxia-inducible factor-1α signaling pathway in ELT-3 cells. | 2015 Jan 5 |
3 |
| 42 |
25542900 | Targeting the metabolic plasticity of multiple myeloma with FDA-approved ritonavir and metformin. | 2015 Mar 1 |
1 |
| 43 |
25906350 | Inhibition of the mammalian target of rapamycin complex 1 signaling pathway reduces itch behaviour in mice. | 2015 Aug |
1 |
| 44 |
26186064 | The antileukemia effect of metformin in the Philadelphia chromosome-positive leukemia cell line and patient primary leukemia cell. | 2015 Oct |
1 |
| 45 |
26344902 | Palmitate activates mTOR/p70S6K through AMPK inhibition and hypophosphorylation of raptor in skeletal muscle cells: Reversal by oleate is similar to metformin. | 2015 Nov |
1 |
| 46 |
26745042 | Benefits of Metformin Use for Cholangiocarcinoma. | 2015 |
1 |
| 47 |
24196830 | Metformin inhibits skin tumor promotion in overweight and obese mice. | 2014 Jan |
2 |
| 48 |
24302004 | Suppression of the mTORC1/STAT3/Notch1 pathway by activated AMPK prevents hepatic insulin resistance induced by excess amino acids. | 2014 Jan 15 |
2 |
| 49 |
24462823 | Metformin: a metabolic disruptor and anti-diabetic drug to target human leukemia. | 2014 May 1 |
1 |
| 50 |
24788596 | Metformin inhibits proliferation and enhances chemosensitivity of intrahepatic cholangiocarcinoma cell lines. | 2014 Jun |
1 |