Pub. Date : 2016 Aug 1
PMID : 27454290
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Treatment of pregnant p53d/d mice with either the antidiabetic drug metformin or the antioxidant resveratrol activated AMPK signaling and inhibited mTORC1 signaling in decidual cells. | Metformin | CREB regulated transcription coactivator 1 | Mus musculus |
2 | Together, these results reveal that p53-dependent coordination of AMPK and mTORC1 signaling controls parturition timing and suggest that metformin and resveratrol have therapeutic potential to prevent PTB. | Metformin | CREB regulated transcription coactivator 1 | Mus musculus |