| 51 |
29706533 | K-Ras Populates Conformational States Differently from Its Isoform H-Ras and Oncogenic Mutant K-RasG12D. | 2018 Jun 5 |
4 |
| 52 |
29808010 | Targeting wild-type KRAS-amplified gastroesophageal cancer through combined MEK and SHP2 inhibition. | 2018 Jul |
3 |
| 53 |
30097175 | Allosteric KRas4B Can Modulate SOS1 Fast and Slow Ras Activation Cycles. | 2018 Aug 21 |
4 |
| 54 |
30104724 | RAS nucleotide cycling underlies the SHP2 phosphatase dependence of mutant BRAF-, NF1- and RAS-driven cancers. | 2018 Sep |
1 |
| 55 |
27909058 | Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner. | 2017 Jan 13 |
1 |
| 56 |
28153726 | K-Ras(G12D)-selective inhibitory peptides generated by random peptide T7 phage display technology. | 2017 Mar 11 |
1 |
| 57 |
28259298 | The cornerstone K-RAS mutation in pancreatic adenocarcinoma: From cell signaling network, target genes, biological processes to therapeutic targeting. | 2017 Mar |
1 |
| 58 |
28597297 | Intrinsic protein disorder in oncogenic KRAS signaling. | 2017 Sep |
1 |
| 59 |
28781124 | Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C. | 2017 Aug 17 |
1 |
| 60 |
29033317 | Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States. | 2017 Dec 21 |
1 |
| 61 |
29199977 | Structural insight into the rearrangement of the switch I region in GTP-bound G12A K-Ras. | 2017 Dec 1 |
11 |
| 62 |
26595770 | The noncoding RNAs SNORD50A and SNORD50B bind K-Ras and are recurrently deleted in human cancer. | 2016 Jan |
1 |
| 63 |
26854029 | KRAS insertion mutations are oncogenic and exhibit distinct functional properties. | 2016 Feb 8 |
6 |
| 64 |
26854235 | KRAS Engages AGO2 to Enhance Cellular Transformation. | 2016 Feb 16 |
1 |
| 65 |
26873344 | K-Ras4B/calmodulin/PI3Kα: A promising new adenocarcinoma-specific drug target? | 2016 Jul |
1 |
| 66 |
26902995 | The Structural Basis of Oncogenic Mutations G12, G13 and Q61 in Small GTPase K-Ras4B. | 2016 Feb 23 |
8 |
| 67 |
26960760 | K-Ras protein as a drug target. | 2016 Mar |
2 |
| 68 |
26977877 | Selective Targeting of the KRAS G12C Mutant: Kicking KRAS When It's Down. | 2016 Mar 14 |
1 |
| 69 |
27057007 | Membrane-associated Ras dimers are isoform-specific: K-Ras dimers differ from H-Ras dimers. | 2016 Jun 15 |
1 |
| 70 |
27410739 | Regulation of K-Ras4B Membrane Binding by Calmodulin. | 2016 Jul 12 |
1 |
| 71 |
27665622 | Impact of G12 Mutations on the Structure of K-Ras Probed by Ultraviolet Photodissociation Mass Spectrometry. | 2016 Oct 12 |
1 |
| 72 |
27845397 | Intrinsic K-Ras dynamics: A novel molecular dynamics data analysis method shows causality between residue pair motions. | 2016 Nov 15 |
2 |
| 73 |
25695162 | Small molecule binding sites on the Ras:SOS complex can be exploited for inhibition of Ras activation. | 2015 Mar 12 |
1 |
| 74 |
25846136 | Differential dynamics of RAS isoforms in GDP- and GTP-bound states. | 2015 Jun |
1 |
| 75 |
25902334 | Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. | 2015 |
2 |
| 76 |
26051715 | GTP-Dependent K-Ras Dimerization. | 2015 Jul 7 |
3 |
| 77 |
26080442 | Ras-GTP dimers activate the Mitogen-Activated Protein Kinase (MAPK) pathway. | 2015 Jun 30 |
1 |
| 78 |
26085527 | The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas. | 2015 Sep |
1 |
| 79 |
26453300 | GTP Binding and Oncogenic Mutations May Attenuate Hypervariable Region (HVR)-Catalytic Domain Interactions in Small GTPase K-Ras4B, Exposing the Effector Binding Site. | 2015 Nov 27 |
4 |
| 80 |
26522388 | Farnesylated and methylated KRAS4b: high yield production of protein suitable for biophysical studies of prenylated protein-lipid interactions. | 2015 Nov 2 |
1 |
| 81 |
29147425 | Polymorphism T81C in H-RAS Oncogene Is Associated With Disease Progression in Imatinib (TKI) Treated Chronic Myeloid Leukemia Patients. | 2015 Apr |
1 |
| 82 |
24338482 | Degradation of activated K-Ras orthologue via K-Ras-specific lysine residues is required for cytokinesis. | 2014 Feb 14 |
3 |
| 83 |
24402942 | Climbing RAS, the everest of oncogenes. | 2014 Jan |
1 |
| 84 |
24470016 | A novel method for the production of fully modified K-Ras 4B. | 2014 |
1 |
| 85 |
23246410 | Rare codons regulate KRas oncogenesis. | 2013 Jan 7 |
1 |
| 86 |
23437064 | Computational analysis of KRAS mutations: implications for different effects on the KRAS p.G12D and p.G13D mutations. | 2013 |
1 |
| 87 |
23737504 | Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function. | 2013 Jun 18 |
1 |
| 88 |
23943869 | Oncogenic K-ras segregates at spatially distinct plasma membrane signaling platforms according to its phosphorylation status. | 2013 Oct 15 |
1 |
| 89 |
24247240 | Differences in the regulation of K-Ras and H-Ras isoforms by monoubiquitination. | 2013 Dec 27 |
1 |
| 90 |
24256730 | K-Ras(G12C) inhibitors allosterically control GTP affinity and effector interactions. | 2013 Nov 28 |
2 |
| 91 |
24297914 | Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors. | 2013 Dec 17 |
2 |
| 92 |
24300897 | PLC-γ and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. | 2013 Dec 3 |
4 |
| 93 |
21768877 | Relationship between expression of ras p21 oncoprotein and mutation status of the K-ras gene in sporadic colorectal cancer patients in Tunisia. | 2012 Mar |
1 |
| 94 |
22205714 | Resistance to selective BRAF inhibition can be mediated by modest upstream pathway activation. | 2012 Feb 15 |
2 |
| 95 |
22302539 | Characterization of a novel KRAS mutation identified in Noonan syndrome. | 2012 Mar |
1 |
| 96 |
22359497 | The role of conserved waters in conformational transitions of Q61H K-ras. | 2012 |
2 |
| 97 |
22721555 | Dissociation of the K-Ras4B/PDEδ complex upon contact with lipid membranes: membrane delivery instead of extraction. | 2012 Jul 18 |
1 |
| 98 |
23027861 | Interplay between menin and K-Ras in regulating lung adenocarcinoma. | 2012 Nov 16 |
1 |
| 99 |
21386094 | Ubiquitination of K-Ras enhances activation and facilitates binding to select downstream effectors. | 2011 Mar 8 |
2 |
| 100 |
22102901 | Galectin-3 mediates cross-talk between K-Ras and Let-7c tumor suppressor microRNA. | 2011 |
4 |