Title : Secreted Glioblastoma Nanovesicles Contain Intracellular Signaling Proteins and Active Ras Incorporated in a Farnesylation-dependent Manner.

Pub. Date : 2017 Jan 13

PMID : 27909058






1 Functional Relationships(s)
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1 Although we initially hypothesized a role for active Ras protein signaling in exosome biogenesis, we found that GTP binding of K-Ras was dispensable for its packaging within extracellular nanovesicles and for the release of Alix. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens