Guanosine Triphosphate

KRAS proto-oncogene, GTPase ; Homo sapiens







145 Article(s)
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Pub. Year
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101 22252770 Concurrent mutation in exons 1 and 2 of the K-ras oncogene in colorectal cancer. 2011 1
102 20532039 Hypoxia activates the K-ras proto-oncogene to stimulate angiogenesis and inhibit apoptosis in colon cancer cells. 2010 Jun 4 2
103 20570890 Genomic and biological characterization of exon 4 KRAS mutations in human cancer. 2010 Jul 15 1
104 20585519 Nucleophosmin and nucleolin regulate K-Ras signaling. 2010 Mar 1
105 20643072 Mathematical modeling of K-Ras nanocluster formation on the plasma membrane. 2010 Jul 21 10
106 20718707 Biomarkers downstream of RAS: a search for robust transcriptional targets. 2010 Dec 1
107 20846262 KRAS gene mutations in lung cancer: particulars established and issues unresolved. 2010 Oct 2
108 19545448 A novel method, digital genome scanning detects KRAS gene amplification in gastric cancers: involvement of overexpressed wild-type KRAS in downstream signaling and cancer cell growth. 2009 Jun 23 3
109 19583261 The hypervariable region of K-Ras4B is responsible for its specific interactions with calmodulin. 2009 Aug 18 1
110 21686750 De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features. 2009 1
111 18291096 Two conformational states of Ras GTPase exhibit differential GTP-binding kinetics. 2008 May 2 1
112 18344980 Tumour maintenance is mediated by eNOS. 2008 Apr 3 1
113 18413234 Galectin-3 regulates RasGRP4-mediated activation of N-Ras and H-Ras. 2008 Jun 3
114 18458061 Electrostatic interactions positively regulate K-Ras nanocluster formation and function. 2008 Jul 2
115 18615637 Galectin-3/MAC-2, Ras and PI3K activate complement receptor-3 and scavenger receptor-AI/II mediated myelin phagocytosis in microglia. 2008 Nov 15 1
116 18701484 K-ras nanoclustering is subverted by overexpression of the scaffold protein galectin-3. 2008 Aug 15 6
117 19064407 Understanding the predictive role of K-ras for epidermal growth factor receptor-targeted therapies in colorectal cancer. 2008 Dec 1
118 17222906 The GAP-related domain of neurofibromin attenuates proliferation and downregulates N- and K-Ras activation in Nf1-negative AML cells. 2007 Aug 1
119 17601930 De novo HRAS and KRAS mutations in two siblings with short stature and neuro-cardio-facio-cutaneous features. 2007 Jul 1
120 17974974 RbAp48 regulates cytoskeletal organization and morphology by increasing K-Ras activity and signaling through mitogen-activated protein kinase. 2007 Nov 1 1
121 16757312 Regulation of the nucleotide state of oncogenic ras proteins by nucleoside diphosphate kinase. 2006 1
122 16923573 Detection of N-RAS and K-RAS in their active GTP-bound form in acute myeloid leukemia without activating RAS mutations. 2006 Jul 2
123 16103080 Galectin-3 regulates a molecular switch from N-Ras to K-Ras usage in human breast carcinoma cells. 2005 Aug 15 1
124 15205467 Galectin-3 augments K-Ras activation and triggers a Ras signal that attenuates ERK but not phosphoinositide 3-kinase activity. 2004 Aug 13 2
125 15215250 Ras activates the epithelial Na(+) channel through phosphoinositide 3-OH kinase signaling. 2004 Sep 3 2
126 15574778 RASSF4/AD037 is a potential ras effector/tumor suppressor of the RASSF family. 2004 Dec 1 1
127 12732644 RASSF2 is a novel K-Ras-specific effector and potential tumor suppressor. 2003 Jul 25 1
128 14506738 High frequency of activated K-ras codon 15 mutant in colorectal carcinomas from Taiwanese patients. 2003 Nov 10 2
129 11799108 A distinct class of dominant negative Ras mutants: cytosolic GTP-bound Ras effector domain mutants that inhibit Ras signaling and transformation and enhance cell adhesion. 2002 Mar 29 1
130 12006650 Coordinated traffic of Grb2 and Ras during epidermal growth factor receptor endocytosis visualized in living cells. 2002 May 1
131 12149263 Galectin-1 augments Ras activation and diverts Ras signals to Raf-1 at the expense of phosphoinositide 3-kinase. 2002 Oct 4 1
132 12354753 Increased K-ras protein and activity in mouse and human lung epithelial cells at confluence. 2002 Sep 2
133 10737386 Decreased GTPase activity of K-ras mutants deriving from human functional adrenocortical tumours. 2000 Mar 2
134 10522044 Ki-ras codon 12 point mutation and p53 mutation in pancreatic diseases. 1999 Jul-Aug 1
135 10624710 Chemopreventive effects of tea extracts and various components on human pancreatic and prostate tumor cells in vitro. 1999 1
136 9657959 Recombinant dengue virus type 1 NS3 protein exhibits specific viral RNA binding and NTPase activity regulated by the NS5 protein. 1998 Jul 5 1
137 9171352 Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro. 1997 May 1 1
138 8820445 Treatment of pancreatic cancer: current limitations, future possibilities. 1996 Mar 2
139 8900189 SMAP, an Smg GDS-associating protein having arm repeats and phosphorylated by Src tyrosine kinase. 1996 Oct 25 1
140 8947526 Phytohemagglutinin-L (PHA-L) lectin surface binding of N-linked beta 1-6 carbohydrate and its relationship to activated mutant ras in human pancreatic cancer cell lines. 1996 Oct 22 2
141 9631088 Spatial dynamics of GFP-tagged proteins investigated by local fluorescence enhancement. 1996 Oct 1
142 7547927 Binding of prenylated and polybasic peptides to membranes: affinities and intervesicle exchange. 1995 Sep 19 1
143 8117282 Kinetic properties of Ash/Grb2-interacting GDP/GTP exchange protein. 1994 Feb 15 2
144 8195145 Different functions of Smg GDP dissociation stimulator and mammalian counterpart of yeast Cdc25. 1994 May 27 18
145 1501882 The functional domain of the stimulatory GDP/GTP exchange protein (smg GDS) which interacts with the C-terminal geranylgeranylated region of rap1/Krev-1/smg p21. 1992 Sep 1