Polyamines

spermidine/spermine N1-acetyltransferase 1 ; Homo sapiens







172 Article(s)
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101 16854216 Peroxisome proliferator-activated receptor gamma and spermidine/spermine N1-acetyltransferase gene expressions are significantly correlated in human colorectal cancer. 2006 Jul 19 3
102 17011643 Spermidine/Spermine N1-Acetyltransferase 2 (SSAT2) functions as a coactivator for NF-kappaB and cooperates with CBP and P/CAF to enhance NF-kappaB-dependent transcription. 2006 Oct 1
103 15845361 Induction of a SSAT isoform in response to hypoxia or iron deficiency and its protective effects on cell death. 2005 May 27 2
104 16207710 Spermine oxidase SMO(PAOh1), Not N1-acetylpolyamine oxidase PAO, is the primary source of cytotoxic H2O2 in polyamine analogue-treated human breast cancer cell lines. 2005 Dec 2 2
105 14750214 Suppression of polyamine catabolism by activated Ki-ras in human colon cancer cells. 2004 Feb 2
106 15096507 Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells. 2004 Jun 25 2
107 15138709 Induction of spermidine/spermine N1-acetyltransferase in breast cancer tissues treated with the polyamine analogue N1, N11-diethylnorspermine. 2004 Aug 3
108 15213272 Overexpression of SSAT in kidney cells recapitulates various phenotypic aspects of kidney ischemia-reperfusion injury. 2004 Jul 2
109 15223770 Accumulation of spermidine/spermine N1-acetyltransferase and alternatively spliced mRNAs as a delayed response of HeLa S3 cells following X-ray irradiation. 2004 May 2
110 15252047 Activated polyamine catabolism depletes acetyl-CoA pools and suppresses prostate tumor growth in TRAMP mice. 2004 Sep 17 2
111 15283699 Spermidine/spermine-N1-acetyltransferase-2 (SSAT2) acetylates thialysine and is not involved in polyamine metabolism. 2004 Nov 15 6
112 15479742 Spermidine/spermine N1-acetyltransferase specifically binds to the integrin alpha9 subunit cytoplasmic domain and enhances cell migration. 2004 Oct 11 3
113 15492267 Spermine acts as a negative regulator of macrophage differentiation in human myeloid leukemia cells. 2004 Oct 15 2
114 12477380 Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion. 2003 Feb 15 3
115 12653639 The role of polyamine catabolism in anti-tumour drug response. 2003 Apr 7
116 12653645 Polyamines as modifiers of genetic risk factors in human intestinal cancers. 2003 Apr 2
117 12697027 Spermidine/spermine N1-acetyltransferase (SSAT) activity in human small-cell lung carcinoma cells following transfection with a genomic SSAT construct. 2003 Jul 15 3
118 12798351 Expression of spermidine/spermine N1-acetyltransferase in HeLa cells is regulated by amino acid sufficiency. 2003 Sep 4
119 12803540 Genomic identification and biochemical characterization of a second spermidine/spermine N1-acetyltransferase. 2003 Aug 1 2
120 12804587 Increased thioredoxin-1 inhibits SSAT expression in MCF-7 human breast cancer cells. 2003 Jun 27 2
121 12827295 Induction of the PAOh1/SMO polyamine oxidase by polyamine analogues in human lung carcinoma cells. 2003 Nov 2
122 12839950 The role of mitogen-activated protein kinase activation in determining cellular outcomes in polyamine analogue-treated human melanoma cells. 2003 Jul 1 2
123 12902979 Loss of inhibitor of apoptosis proteins as a determinant of polyamine analog-induced apoptosis in human melanoma cells. 2003 Aug 7 2
124 14506281 Cyclooxygenase-independent induction of apoptosis by sulindac sulfone is mediated by polyamines in colon cancer. 2003 Nov 28 2
125 14573765 Small interfering RNA suppression of polyamine analog-induced spermidine/spermine n1-acetyltransferase. 2003 Nov 3
126 11846806 Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N(1),N(11)-diethylnorspermine. 2002 Feb 1
127 12141946 Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell origin. 2002 Nov 1 2
128 12215835 Gene dosage of the spermidine/spermine N(1)-acetyltransferase ( SSAT) gene with putrescine accumulation in a patient with a Xp21.1p22.12 duplication and keratosis follicularis spinulosa decalvans (KFSD). 2002 Sep 1
129 12427553 Functional characterization of the human spermidine/spermine N(1)-acetyltransferase gene promoter. 2002 Dec 12 2
130 11166157 Differential induction of spermidine/spermine N1-acetyltransferase activity in cisplatin-sensitive and -resistant ovarian cancer cells in response to N1,N12-bis(ethyl)spermine involves transcriptional and post-transcriptional regulation. 2001 Jan 1
131 11171097 Manipulation of the expression of regulatory genes of polyamine metabolism results in specific alterations of the cell-cycle progression. 2001 Feb 15 2
132 11256947 Characterization of the interaction between the transcription factors human polyamine modulated factor (PMF-1) and NF-E2-related factor 2 (Nrf-2) in the transcriptional regulation of the spermidine/spermine N1-acetyltransferase (SSAT) gene. 2001 Apr 1 1
133 11485561 Polyamine analogues inhibit the ubiquitination of spermidine/spermine N1-acetyltransferase and prevent its targeting to the proteasome for degradation. 2001 Aug 15 4
134 11522638 Apoptotic signaling in polyamine analogue-treated SK-MEL-28 human melanoma cells. 2001 Sep 1 1
135 10978316 Effects of conditional overexpression of spermidine/spermine N1-acetyltransferase on polyamine pool dynamics, cell growth, and sensitivity to polyamine analogs. 2000 Dec 8 6
136 10212127 1-(N-alkylamino)-11-(N-ethylamino)-4,8-diazaundecanes: simple synthetic polyamine analogues that differentially alter tubulin polymerization. 1999 Apr 22 2
137 10419538 Cloning and characterization of human polyamine-modulated factor-1, a transcriptional cofactor that regulates the transcription of the spermidine/spermine N(1)-acetyltransferase gene. 1999 Jul 30 4
138 10430062 The induction of spermidine/spermine N1-acetyltransferase (SSAT) is a common event in the response of human primary non-small cell lung carcinomas to exposure to the new antitumor polyamine analogue N1,N11-bis(ethyl)norspermine. 1999 Jul 4
139 9462700 Inhibition of cell growth in CaCO2 cells by the polyamine analogue N1,N12-bis(ethyl)spermine is preceded by a reduction in MYC oncoprotein levels. 1998 Mar 1
140 9480841 Significant increases in the steady states of putrescine and spermidine/spermine N1-acetyltransferase mRNA in HeLa cells accompanied by growth arrest. 1998 Feb 13 1
141 9605436 Induction of spermidine/spermine N1-acetyltransferase in human cancer cells in response to increased production of reactive oxygen species. 1998 Apr 1 1
142 9717831 Two active copies of the X-linked gene spermidine/spermine N1-acetyltransferase (SSAT) in a female lung cancer cell line are associated with an increase in sensitivity to an antitumor polyamine analogue. 1998 Aug 10
143 9724091 N1,N12-bis(ethyl)spermine effect on growth of cis-diamminedichloroplatinum(II)-sensitive and -resistant human ovarian-carcinoma cell lines. 1998 Sep 25 2
144 9852135 The identification of a cis-element and a trans-acting factor involved in the response to polyamines and polyamine analogues in the regulation of the human spermidine/spermine N1-acetyltransferase gene transcription. 1998 Dec 18 4
145 9115288 Proteasomal degradation of spermidine/spermine N1-acetyltransferase requires the carboxyl-terminal glutamic acid residues. 1997 May 2 8
146 9224814 Structural basis for differential induction of spermidine/spermine N1-acetyltransferase activity by novel spermine analogs. 1997 Jul 2
147 9326648 The role of polyamine catabolism in polyamine analogue-induced programmed cell death. 1997 Oct 14 2
148 8573111 Differential transcription of the human spermidine/spermine N1-acetyltransferase (SSAT) gene in human lung carcinoma cells. 1996 Jan 15 6
149 8702554 RGFGIGS is an amino acid sequence required for acetyl coenzyme A binding and activity of human spermidine/spermine N1acetyltransferase. 1996 Aug 2 2
150 8706937 Differential post-transcriptional control of ornithine decarboxylase and spermidine-spermine N1-acetyltransferase by polyamines. 1996 Aug 5 5