Title : Structural basis for differential induction of spermidine/spermine N1-acetyltransferase activity by novel spermine analogs.

Pub. Date : 1997 Jul

PMID : 9224814






2 Functional Relationships(s)
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1 The spermine analog N1,N11-diethylnorspermine (DE-333, also known as DENSPM or BENSPM) is regarded as the most potent known inducer of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT), increasing activity by more than 200- to 1000-fold in certain cell types. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
2 The spermine analog N1,N11-diethylnorspermine (DE-333, also known as DENSPM or BENSPM) is regarded as the most potent known inducer of the polyamine catabolic enzyme, spermidine/spermine N1-acetyltransferase (SSAT), increasing activity by more than 200- to 1000-fold in certain cell types. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens