Title : The role of polyamine catabolism in polyamine analogue-induced programmed cell death.

Pub. Date : 1997 Oct 14

PMID : 9326648






2 Functional Relationships(s)
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Protein Name
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1 CPENSpm treatment results in the superinduction of the polyamine catabolic enzyme spermidine/spermine N1-acetyltransferase (SSAT) in sensitive cell types and has been demonstrated to induce programmed cell death (PCD). Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
2 The catalysis of polyamines by the SSAT/polyamine oxidase (PAO) pathway produces H2O2 as one product, suggesting that PCD produced by CPENSpm may be, in part, due to oxidative stress as a result of H2O2 production. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens