Polyamines

spermidine/spermine N1-acetyltransferase 1 ; Homo sapiens







172 Article(s)
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51 21809078 Tissue-specific alternative splicing of spermidine/spermine N1-acetyltransferase. 2012 Feb 7
52 21809081 Novel anti-apoptotic effect of the retinoblastoma protein: implications for polyamine analogue toxicity. 2012 Feb 4
53 21818565 Polyamine flux analysis by determination of heavy isotope incorporation from 13C, 15N-enriched amino acids into polyamines by LC-MS/MS. 2012 Feb 1
54 22170508 Increased recycling of polyamines is associated with global DNA hypomethylation in rheumatoid arthritis synovial fibroblasts. 2012 Jun 1
55 22179681 Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma. 2012 Apr 2
56 22294330 Silencing of the polyamine catabolic key enzyme SSAT prevents CDK inhibitor-induced apoptosis in Caco-2 colon cancer cells. 2012 Apr 3
57 22354986 Polyamine-regulated translation of spermidine/spermine-N1-acetyltransferase. 2012 Apr 8
58 22579641 Chemically induced oxidative stress increases polyamine levels by activating the transcription of ornithine decarboxylase and spermidine/spermine-N1-acetyltransferase in human hepatoma HUH7 cells. 2012 Sep 3
59 23021806 A mass spectrometric method to determine activities of enzymes involved in polyamine catabolism. 2012 Oct 20 1
60 20443003 Combination effects of platinum drugs and N1, N11 diethylnorspermine on spermidine/spermine N1-acetyltransferase, polyamines and growth inhibition in A2780 human ovarian carcinoma cells and their oxaliplatin and cisplatin-resistant variants. 2011 Feb 1
61 21318890 High-resolution capillary gas chromatography in combination with mass spectrometry for quantification of three major polyamines in postmortem brain cortex. 2011 2
62 19727732 The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines. 2010 May 3
63 19956992 Activated polyamine catabolism leads to low cholesterol levels by enhancing bile acid synthesis. 2010 Feb 2
64 20031193 Spermidine/spermine N1-acetyltranferase modulation by novel folate cycle inhibitors in cisplatin-sensitive and -resistant human ovarian cancer cell lines. 2010 May 2
65 20212040 Suppression of exogenous gene expression by spermidine/spermine N1-acetyltransferase 1 (SSAT1) cotransfection. 2010 May 14 3
66 20388096 Lactobacillus rhamnosus GG influences polyamine metabolism in HGC-27 gastric cancer cell line: a strategy toward nutritional approach to chemoprevention of gastric cance. 2010 2
67 20460526 Androgen receptor requires JunD as a coactivator to switch on an oxidative stress generation pathway in prostate cancer cells. 2010 Jun 1 3
68 20514439 Characterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells. 2010 Jul 1
69 18759322 Positive association between SAT-1 -1415T/C polymorphism and anxiety. 2009 Jun 5 1
70 19152344 Profiling brain expression of the spermidine/spermine N1-acetyltransferase 1 (SAT1) gene in suicide. 2009 Oct 5 5
71 19162121 SAT-1 -1415T/C polymorphism and susceptibility to schizophrenia. 2009 Mar 17 2
72 19589128 Polyamine catabolism and disease. 2009 Jul 15 4
73 19685053 The polyamine analog PG11047 potentiates the antitumor activity of cisplatin and bevacizumab in preclinical models of lung and prostate cancer. 2009 Dec 2
74 19686286 Adenovirus vector-mediated upregulation of spermidine /spermine N1-acetyltransferase impairs human gastric cancer growth in vitro and in vivo. 2009 Nov 2
75 19956562 Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migration. 2009 Nov 20 1
76 20095967 Polyamine homoeostasis. 2009 Nov 4 8
77 17920945 Subcellular distribution of spermidine/spermine N1-acetyltransferase. 2008 Jan 2
78 18089555 Polyamine acetylation modulates polyamine metabolic flux, a prelude to broader metabolic consequences. 2008 Feb 15 6
79 18301893 In vitro and in vivo effects of the conformationally restricted polyamine analogue CGC-11047 on small cell and non-small cell lung cancer cells. 2008 Dec 1
80 18349109 Spermidine/spermine-N(1)-acetyltransferase: a key metabolic regulator. 2008 Jun 8
81 18430370 Adenovirus-mediated expression of SSAT inhibits colorectal cancer cell growth in vitro. 2008 May 1
82 18571584 A polyamine analog bismethylspermine ameliorates severe pancreatitis induced by intraductal infusion of taurodeoxycholate. 2008 Jul 2
83 18660501 Identification and characterization of a diamine exporter in colon epithelial cells. 2008 Sep 26 1
84 18690703 The crystal structure of spermidine/spermine N1-acetyltransferase in complex with spermine provides insights into substrate binding and catalysis. 2008 Sep 2 1
85 18949426 Adenovirus-mediated expression of spermidine/spermine N1-acetyltransferase gene induces S-phase arrest in human colorectal cancer cells. 2008 Nov 2
86 19036131 Effects of small interfering RNA targeting thymidylate synthase on survival of ACC3 cells from salivary adenoid cystic carcinoma. 2008 Nov 26 2
87 17021820 Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells. 2007 May 3
88 17065202 Spermidine/spermine N1-acetyltransferase overexpression in kidney epithelial cells disrupts polyamine homeostasis, leads to DNA damage, and causes G2 arrest. 2007 Mar 5
89 17237273 The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells. 2007 Jan 3
90 17371265 Inflammation and polyamine catabolism: the good, the bad and the ugly. 2007 Apr 2
91 17382924 Role of polyamines in myocardial ischemia/reperfusion injury and their interactions with nitric oxide. 2007 May 21 1
92 17516632 Mechanistic and structural analysis of human spermidine/spermine N1-acetyltransferase. 2007 Jun 19 4
93 17637456 Polyamine-modulated factor 1 represses glucocorticoid receptor activity. 2007 Sep 14 2
94 17690107 Polyamine-dependent regulation of spermidine-spermine N1-acetyltransferase mRNA translation. 2007 Sep 28 9
95 16262603 Induction of spermidine/spermine N1-acetyltransferase (SSAT) by aspirin in Caco-2 colon cancer cells. 2006 Feb 15 3
96 16452302 Genetic manipulation of polyamine catabolism in rodents. 2006 Feb 4
97 16455797 Structures of wild-type and mutant human spermidine/spermine N1-acetyltransferase, a potential therapeutic drug target. 2006 Feb 14 4
98 16637064 Inactivation of IkappaB contributes to transcriptional activation of spermidine/spermine N(1)-acetyltransferase. 2006 Sep 2
99 16757480 Tumor necrosis factor alpha induces spermidine/spermine N1-acetyltransferase through nuclear factor kappaB in non-small cell lung cancer cells. 2006 Aug 25 2
100 16809818 Polyamine-regulated unproductive splicing and translation of spermidine/spermine N1-acetyltransferase. 2006 Aug 6