Title : Genomic identification and biochemical characterization of the mammalian polyamine oxidase involved in polyamine back-conversion.

Pub. Date : 2003 Feb 15

PMID : 12477380






3 Functional Relationships(s)
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Protein Name
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1 In the polyamine back-conversion pathway, spermine and spermidine are first acetylated by spermidine/spermine N1 -acetyltransferase (SSAT) and then oxidized by polyamine oxidase (PAO) to produce spermidine and putrescine respectively. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
2 In the polyamine back-conversion pathway, spermine and spermidine are first acetylated by spermidine/spermine N1 -acetyltransferase (SSAT) and then oxidized by polyamine oxidase (PAO) to produce spermidine and putrescine respectively. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
3 In Northern blot analysis, PAO mRNA was much less abundant in HEK-293 cells than SMO or SSAT mRNA, and all three were differentially induced in a similar manner by selected polyamine analogues. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens