Title : Differential transcription of the human spermidine/spermine N1-acetyltransferase (SSAT) gene in human lung carcinoma cells.

Pub. Date : 1996 Jan 15

PMID : 8573111






6 Functional Relationships(s)
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1 The expression of spermidine/spermine N1-acetyltransferase (SSAT), the rate-limiting enzyme in the catabolism of polyamines, is highly regulated by a number of factors including the natural polyamines and their analogues. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
2 The expression of spermidine/spermine N1-acetyltransferase (SSAT), the rate-limiting enzyme in the catabolism of polyamines, is highly regulated by a number of factors including the natural polyamines and their analogues. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
3 The expression of spermidine/spermine N1-acetyltransferase (SSAT), the rate-limiting enzyme in the catabolism of polyamines, is highly regulated by a number of factors including the natural polyamines and their analogues. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
4 The expression of spermidine/spermine N1-acetyltransferase (SSAT), the rate-limiting enzyme in the catabolism of polyamines, is highly regulated by a number of factors including the natural polyamines and their analogues. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
5 The phenotype-specific cytotoxicity that occurs in response to a class of polyamine analogues, the diethylpolyamines, is associated with a phenotype-specific superinduction of SSAT in human non-small-cell lung carcinomas, whereas in non-responding cell types, including the small-cell lung carcinomas, the superinduction of SSAT does not occur. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens
6 The phenotype-specific cytotoxicity that occurs in response to a class of polyamine analogues, the diethylpolyamines, is associated with a phenotype-specific superinduction of SSAT in human non-small-cell lung carcinomas, whereas in non-responding cell types, including the small-cell lung carcinomas, the superinduction of SSAT does not occur. Polyamines spermidine/spermine N1-acetyltransferase 1 Homo sapiens