Leukotriene A4






110 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 1312812 On the nature of leukotriene C4 synthase in human platelets. Arch Biochem Biophys 1992 Apr 2
2 1331064 Mechanism-based inactivation of leukotriene A4 hydrolase/aminopeptidase by leukotriene A4. Mass spectrometric and kinetic characterization. J Biol Chem 1992 Nov 15 1
3 1429555 Reversible membrane association of neutrophil 5-lipoxygenase is accompanied by retention of activity and a change in substrate specificity. J Biol Chem 1992 Nov 5 1
4 1780443 Purification of natural killer-like Kurloff cells and arachidonic acid metabolism. Prostaglandins 1991 Sep 1
5 1848236 Characterization of the activity of purified recombinant human 5-lipoxygenase in the absence and presence of leukocyte factors. J Biol Chem 1991 Mar 15 1
6 2168394 Mechanism-based inactivation of leukotriene A4 hydrolase during leukotriene B4 formation by human erythrocytes. J Biol Chem 1990 Sep 5 1
7 2300172 Identification and isolation of a membrane protein necessary for leukotriene production. Nature 1990 Jan 18 1
8 2649885 Native and mutant 5-lipoxygenase expression in a baculovirus/insect cell system. Proc Natl Acad Sci U S A 1989 Apr 1
9 2823886 Kinetics of leukotriene A4 synthesis by 5-lipoxygenase from rat polymorphonuclear leukocytes. Biochemistry 1987 Sep 8 2
10 2829972 Enzymatic formation of 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid: kinetics of the reaction and stereochemistry of the product. Biochim Biophys Acta 1988 Feb 19 2
11 2837199 Human B and T lymphocytes convert leukotriene A4 into leukotriene B4. Biochem Biophys Res Commun 1988 May 31 1
12 2996528 Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase. Biochem Biophys Res Commun 1985 Sep 16 3
13 3006030 Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities. Proc Natl Acad Sci U S A 1986 Feb 1
14 3006048 Erythrocyte-neutrophil interactions: formation of leukotriene B4 by transcellular biosynthesis. Proc Natl Acad Sci U S A 1986 Mar 1
15 3009453 Leukotriene A4. Enzymatic conversion into 5,6-dihydroxy-7,9,11,14-eicosatetraenoic acid by mouse liver cytosolic epoxide hydrolase. J Biol Chem 1986 May 15 2
16 3012557 Characterization of leukotriene A4 synthase from murine mast cells: evidence for its identity to arachidonate 5-lipoxygenase. Proc Natl Acad Sci U S A 1986 Jun 1
17 3020619 Stereoselective hydrogen abstraction in leukotriene A4 synthesis by purified 5-lipoxygenase of porcine leukocytes. Prostaglandins 1986 Jul 2
18 3031215 Enzymic synthesis of leukotriene B4 in guinea pig brain. J Neurochem 1987 May 2
19 3036460 An elucidation of the arachidonic acid cascade. Discovery of prostaglandins, thromboxane and leukotrienes. Drugs 1987 1
20 3121320 Purification of a new acidic glutathione S-transferase, GST-Yn1Yn1, with a high leukotriene-C4 synthase activity from rat brain. Eur J Biochem 1987 Dec 30 2
21 6254506 Identification of the C(6)-S-conjugate of leukotriene A with cysteine as a naturally occurring slow reacting substance of anaphylaxis (SRS-A). Importance of the 11-cis-geometry for biological activity. Biochem Biophys Res Commun 1980 Sep 16 1
22 6322165 Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Proc Natl Acad Sci U S A 1984 Feb 2
23 6329309 Metabolism of arachidonic acid by human neutrophils. Characterization of the enzymatic reactions that lead to the synthesis of leukotriene B4. Biochim Biophys Acta 1984 Jun 6 1
24 6811315 Selective inhibition of 5-lipoxygenase by 5,6-methanoleukotriene A4, a stable analogue of leukotriene A4. FEBS Lett 1982 Jun 21 1
25 7582974 Investigation of the inhibition of leukotriene A4 hydrolase. Bioorg Med Chem 1995 Jul 1
26 7649151 Evidence for a catalytic role of tyrosine 383 in the peptidase reaction of leukotriene A4 hydrolase. Eur J Biochem 1995 Aug 1 1
27 7840802 Enhancement of leukotriene A4 biosynthesis in neutrophils from patients with rheumatoid arthritis after a single glucocorticoid dose. Biochem Pharmacol 1995 Jan 18 1
28 7914721 Human epidermis transforms exogenous leukotriene A4 into peptide leukotrienes: possible role in transcellular metabolism. Arch Dermatol Res 1994 1
29 7929400 Eosinophil 15-lipoxygenase is a leukotriene A4 synthase. J Biol Chem 1994 Oct 28 2
30 7938075 5-Lipoxygenase: enzyme expression and regulation of activity. Pharm Acta Helv 1994 Jul 1
31 8052639 Expression cloning of a cDNA for human leukotriene C4 synthase, an integral membrane protein conjugating reduced glutathione to leukotriene A4. Proc Natl Acad Sci U S A 1994 Aug 2 1
32 8157657 The bifunctional enzyme leukotriene-A4 hydrolase is an arginine aminopeptidase of high efficiency and specificity. J Biol Chem 1994 Apr 15 1
33 8215451 Identification of 5-keto-(7E,9E,11Z,14Z)-eicosatetraenoic acid as a novel nonenzymatic rearrangement product of leukotriene A4. Arch Biochem Biophys 1993 Nov 1 2
34 8269937 Coupling of recombinant 5-lipoxygenase and leukotriene A4 hydrolase activities and transcellular metabolism of leukotriene A4 in Sf9 insect cells. Eur J Biochem 1993 Dec 1 1
35 8300592 Irreversible inactivation of 5-lipoxygenase by leukotriene A4. Characterization of product inactivation with purified enzyme and intact leukocytes. J Biol Chem 1994 Jan 28 7
36 8305492 Stimulation of lipoxin synthesis from leukotriene A4 by endogenously formed 12-hydroperoxyeicosatetraenoic acid in activated human platelets. Biochim Biophys Acta 1994 Jan 20 1
37 8344271 5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase. Eur J Biochem 1993 Jul 1 1
38 8395245 Interfacial catalysis and production of a high ratio of leukotriene A4 to 5-HPETE by 5-lipoxygenase in a coupled assay with phospholipase A2. J Lipid Mediat 1993 Mar-Apr 2
39 8555027 Characterization of the aminopeptidase activity of epidermal leukotriene A4 hydrolase against the opioid dynorphin fragment 1-7. Br J Dermatol 1995 Nov 2
40 8706657 Formation of a novel enzymatic metabolite of leukotriene A4 in tissues of Xenopus laevis. Eur J Biochem 1996 Jun 15 1
41 8706658 Molecular cloning, expression and characterization of mouse leukotriene C4 synthase. Eur J Biochem 1996 Jun 15 1
42 8798687 Leukotriene A4 hydrolase, mutation of tyrosine 378 allows conversion of leukotriene A4 into an isomer of leukotriene B4. J Biol Chem 1996 Oct 4 2
43 9096329 Aminopeptidase B from the rat testis is a bifunctional enzyme structurally related to leukotriene-A4 hydrolase. Proc Natl Acad Sci U S A 1997 Apr 1 2
44 9153254 Site-directed mutagenesis of human leukotriene C4 synthase. J Biol Chem 1997 May 23 2
45 9209681 Human melanoma cells generate leukotrienes B4 and C4 from leukotriene A4. Arch Dermatol Res 1997 May 1
46 9265777 Immobilization of potato tuber lipoxygenase on oxirane acrylic beads. Biotechnol Prog 1997 Jul-Aug 1
47 9287304 Mutation of tyrosine 383 in leukotriene A4 hydrolase allows conversion of leukotriene A4 into 5S,6S-dihydroxy-7,9-trans-11,14-cis-eicosatetraenoic acid. Implications for the epoxide hydrolase mechanism. J Biol Chem 1997 Sep 12 1
48 9342232 Molecular cloning of the gene for mouse leukotriene-C4 synthase. Eur J Biochem 1997 Sep 15 2
49 9554994 Kinetic mechanism of glutathione conjugation to leukotriene A4 by leukotriene C4 synthase. Biochim Biophys Acta 1998 Mar 30 1
50 9609696 Calcium is not required for 5-lipoxygenase activity at high phosphatidyl choline vesicle concentrations. Biochemistry 1998 Jun 2 1