Title : Human epidermis transforms exogenous leukotriene A4 into peptide leukotrienes: possible role in transcellular metabolism.

Pub. Date : 1994

PMID : 7914721






1 Functional Relationships(s)
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1 These results indicate that human skin contains leukotriene C4 synthase activity capable of producing significant amounts of leukotriene C4 from leukotriene A4, and that the keratinocytes may play a more active role in peptide leukotriene formation in the skin than previously thought. Leukotriene A4 leukotriene C4 synthase Homo sapiens