Title : Leukotriene A5 is a substrate and an inhibitor of rat and human neutrophil LTA4 hydrolase.

Pub. Date : 1985 Sep 16

PMID : 2996528






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Both rat and human LTA4 hydrolase utilized leukotriene A5 less effectively as a substrate than leukotriene A4. Leukotriene A4 leukotriene A4 hydrolase Homo sapiens
2 Purified rat neutrophil LTA4 hydrolase incubated with 100 microM leukotriene A5 produced 22 nmol LTB5/min/mg protein and when incubated with 100 microM leukotriene A4 produced 50 nmol LTB4/min/mg protein. Leukotriene A4 leukotriene A4 hydrolase Rattus norvegicus
3 Leukotriene A5 was an inhibitor of the formation of leukotriene B4 from leukotriene A4 by both the rat and human neutrophil LTA4 hydrolase. Leukotriene A4 leukotriene A4 hydrolase Homo sapiens