Title : 5-lipoxygenase-activating protein stimulates the utilization of arachidonic acid by 5-lipoxygenase.

Pub. Date : 1993 Jul 1

PMID : 8344271






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 5-Lipoxygenase (5-LO) and its activating protein (FLAP) are both required for cellular leukotriene (LT) synthesis, with 5-LO catalyzing both the synthesis of (5S)-5-hydroperoxy-6,8,11,14-eicosatetraenoic acid (5-HPETE) from arachidonic acid and the subsequent synthesis of LTA4 from 5-HPETE. Leukotriene A4 arachidonate 5-lipoxygenase activating protein Homo sapiens