Pub. Date : 1994 Oct 28
PMID : 7929400
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 5-Lipoxygenase is the first committed enzyme in the leukotriene biosynthetic pathway and is known to catalyze not only the first oxygenation of arachidonate to form 5(S)-hydroperoxyeicosatetraenoic acid (5(S)-HPETE), but also dehydration of this intermediate into leukotriene A4 (LTA4) by an activity termed leukotriene A4 synthase. | Leukotriene A4 | arachidonate 5-lipoxygenase | Homo sapiens |
| 2 | 5-Lipoxygenase is the first committed enzyme in the leukotriene biosynthetic pathway and is known to catalyze not only the first oxygenation of arachidonate to form 5(S)-hydroperoxyeicosatetraenoic acid (5(S)-HPETE), but also dehydration of this intermediate into leukotriene A4 (LTA4) by an activity termed leukotriene A4 synthase. | Leukotriene A4 | arachidonate 5-lipoxygenase | Homo sapiens |