Title : Stimulation of lipoxin synthesis from leukotriene A4 by endogenously formed 12-hydroperoxyeicosatetraenoic acid in activated human platelets.

Pub. Date : 1994 Jan 20

PMID : 8305492






1 Functional Relationships(s)
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1 Human platelets are devoid of 5-lipoxygenase activity but convert exogenous leukotriene A4 (LTA4) either by a specific LTC4 synthase to leukotriene C4 or via a 12-lipoxygenase mediated reaction to lipoxins. Leukotriene A4 leukotriene C4 synthase Homo sapiens