Title : Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid.

Pub. Date : 1984 Feb

PMID : 6322165






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Enzyme with dual lipoxygenase activities catalyzes leukotriene A4 synthesis from arachidonic acid. Leukotriene A4 probable linoleate 9S-lipoxygenase 5 Solanum tuberosum
2 Several experiments, including those with lipoxygenase inhibitors, heat treatment, and competitive inhibition, indicated that both the 5-lipoxygenase and leukotriene A4 synthase activities resided in the same protein and that the formation of leukotriene A4 from 5-HPETE was catalyzed by the 8-lipoxygenase activity of the enzyme. Leukotriene A4 probable linoleate 9S-lipoxygenase 5 Solanum tuberosum