bis(3',5')-cyclic diguanylic acid






112 Article(s)
Download
PMID
Title
Journal
Pub. Date
#Total Relationship(s)
1 7487952 The novel cyclic dinucleotide 3'-5' cyclic diguanylic acid binds to p21ras and enhances DNA synthesis but not cell replication in the Molt 4 cell line. Biochem J 1995 Nov 1 1
2 10037160 Elevated expression of the CD4 receptor and cell cycle arrest are induced in Jurkat cells by treatment with the novel cyclic dinucleotide 3',5'-cyclic diguanylic acid. FEBS Lett 1999 Feb 5 2
3 15995192 The ubiquitous protein domain EAL is a cyclic diguanylate-specific phosphodiesterase: enzymatically active and inactive EAL domains. J Bacteriol 2005 Jul 1
4 16530465 Cyclic di-GMP as a second messenger. Curr Opin Microbiol 2006 Apr 1
5 17187906 The bacterial second messenger cyclic diGMP exhibits potent adjuvant properties. Vaccine 2007 Feb 9 2
6 17208514 c-di-GMP-mediated regulation of virulence and biofilm formation. Curr Opin Microbiol 2007 Feb 1
7 17277122 Bacterial c-di-GMP is an immunostimulatory molecule. J Immunol 2007 Feb 15 11
8 17335280 Ultraviolet resonance Raman evidence for utilization of the heme 6-propionate hydrogen-bond network in signal transmission from heme to protein in Ec DOS protein. J Am Chem Soc 2007 Mar 28 1
9 17567766 The bacterial second messenger cdiGMP exhibits promising activity as a mucosal adjuvant. Clin Vaccine Immunol 2007 Aug 1
10 18450754 Roles of Arg-97 and Phe-113 in regulation of distal ligand binding to heme in the sensor domain of Ec DOS protein. Resonance Raman and mutation study. J Biol Chem 2008 Jul 4 1
11 18640167 c-di-GMP is an effective immunomodulator and vaccine adjuvant against pneumococcal infection. Vaccine 2008 Aug 26 1
12 19053256 Ligand binding to the Fe(III)-protoporphyrin IX complex of phosphodiesterase from Escherichia coli (Ec DOS) markedly enhances catalysis of cyclic di-GMP: roles of Met95, Arg97, and Phe113 of the putative heme distal side in catalytic regulation and ligand binding. Biochemistry 2008 Dec 16 3
13 19170727 HD-GYP domain proteins regulate biofilm formation and virulence in Pseudomonas aeruginosa. Environ Microbiol 2009 May 2
14 19400772 Two small ncRNAs jointly govern virulence and transmission in Legionella pneumophila. Mol Microbiol 2009 May 1
15 19494585 Prevailing concepts of c-di-GMP signaling. Contrib Microbiol 2009 1
16 19764732 An oxygen-sensing diguanylate cyclase and phosphodiesterase couple for c-di-GMP control. Biochemistry 2009 Oct 20 1
17 21278272 Indirect modulation of the intracellular c-Di-GMP level in Shewanella oneidensis MR-1 by MxdA. Appl Environ Microbiol 2011 Mar 3
18 21600260 Intranasal c-di-GMP-adjuvanted plant-derived H5 influenza vaccine induces multifunctional Th1 CD4+ cells and strong mucosal and systemic antibody responses in mice. Vaccine 2011 Jul 12 1
19 21670168 Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burgdorferi. Infect Immun 2011 Aug 3
20 21710212 Large-scale production of the immunomodulator c-di-GMP from GMP and ATP by an enzymatic cascade. Appl Biochem Biotechnol 2011 Oct 1
21 21738477 Cyclic di-GMP is essential for the survival of the lyme disease spirochete in ticks. PLoS Pathog 2011 Jun 1
22 21813776 MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP. J Immunol 2011 Sep 1 3
23 21992096 A multi-repeat adhesin of the phytopathogen, Pectobacterium atrosepticum, is secreted by a Type I pathway and is subject to complex regulation involving a non-canonical diguanylate cyclase. Mol Microbiol 2011 Nov 5
24 22579474 Structural analysis of the STING adaptor protein reveals a hydrophobic dimer interface and mode of cyclic di-GMP binding. Immunity 2012 Jun 29 12
25 22810222 Structures of the PelD cyclic diguanylate effector involved in pellicle formation in Pseudomonas aeruginosa PAO1. J Biol Chem 2012 Aug 31 5
26 22869119 Crystallization studies of the murine c-di-GMP sensor protein STING. Acta Crystallogr Sect F Struct Biol Cryst Commun 2012 Aug 1 2
27 23121983 Evidence for cyclic diguanylate as a vaccine adjuvant with novel immunostimulatory activities. Cell Immunol 2012 Jul-Aug 4
28 23142775 The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol 2012 Dec 13
29 23478317 Study of the response regulator Rrp1 reveals its regulatory role in chitobiose utilization and virulence of Borrelia burgdorferi. Infect Immun 2013 May 2
30 23604073 Species-specific detection of the antiviral small-molecule compound CMA by STING. EMBO J 2013 May 15 2
31 23704787 FimK regulation on the expression of type 1 fimbriae in Klebsiella pneumoniae CG43S3. Microbiology (Reading) 2013 Jul 1
32 24008845 Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome. EMBO Rep 2013 Oct 3
33 24204993 Single nucleotide polymorphisms of human STING can affect innate immune response to cyclic dinucleotides. PLoS One 2013 1
34 24218478 Cyclic Di-GMP receptor PlzA controls virulence gene expression through RpoS in Borrelia burgdorferi. Infect Immun 2014 Jan 1
35 24291602 LTQ-XL mass spectrometry proteome analysis expands the Pseudomonas aeruginosa AmpR regulon to include cyclic di-GMP phosphodiesterases and phosphoproteins, and identifies novel open reading frames. J Proteomics 2014 Jan 16 2
36 24391220 An alternative splicing isoform of MITA antagonizes MITA-mediated induction of type I IFNs. J Immunol 2014 Feb 1 4
37 24560620 NLRC3, a member of the NLR family of proteins, is a negative regulator of innate immune signaling induced by the DNA sensor STING. Immunity 2014 Mar 20 2
38 24612375 BrlR from Pseudomonas aeruginosa is a c-di-GMP-responsive transcription factor. Mol Microbiol 2014 May 1
39 24727060 A new adjuvant delivery system 'cyclic di-GMP/YSK05 liposome' for cancer immunotherapy. J Control Release 2014 Jun 28 12
40 24731807 A new adjuvanted nanoparticle-based H1N1 influenza vaccine induced antigen-specific local mucosal and systemic immune responses after administration into the lung. Vaccine 2014 May 30 2
41 24874800 Polyphosphate, cyclic AMP, guanosine tetraphosphate, and c-di-GMP reduce in vitro Lon activity. Bioengineered 2014 Jul-Aug 5
42 24913717 STING ligand c-di-GMP improves cancer vaccination against metastatic breast cancer. Cancer Immunol Res 2014 Sep 3
43 25300859 STING contributes to antiglioma immunity via triggering type I IFN signals in the tumor microenvironment. Cancer Immunol Res 2014 Dec 2
44 25487675 Backbone resonance assignments of the 54 kDa dimeric C-terminal domain of murine STING in complex with DMXAA. Biomol NMR Assign 2015 Oct 4
45 25776036 The cytosolic sensor, DDX41, activates antiviral and inflammatory immunity in response to stimulation with double-stranded DNA adherent cells of the olive flounder, Paralichthys olivaceus. Fish Shellfish Immunol 2015 Jun 2
46 25843711 Bacterial c-di-GMP affects hematopoietic stem/progenitors and their niches through STING. Cell Rep 2015 Apr 7 5
47 25894344 Global Regulator MorA Affects Virulence-Associated Protease Secretion in Pseudomonas aeruginosa PAO1. PLoS One 2015 1
48 25898005 The mucosal adjuvant cyclic di-GMP enhances antigen uptake and selectively activates pinocytosis-efficient cells in vivo. Elife 2015 Apr 21 5
49 26043087 A label-free and self-assembled electrochemical biosensor for highly sensitive detection of cyclic diguanylate monophosphate (c-di-GMP) based on RNA riboswitch. Anal Chim Acta 2015 Jul 2 1
50 26195595 Function of the Histone-Like Protein H-NS in Motility of Escherichia coli: Multiple Regulatory Roles Rather than Direct Action at the Flagellar Motor. J Bacteriol 2015 Oct 1